Medisinsk forskning på cannabis
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EDEMA (20)
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Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy induced painful neuropathy
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The cannabinoid receptor-2 is involved in allergic inflammation
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Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxicischemic brain injury
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Activation of Cannabinoid CB2 Receptor-Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury
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Sex differences in anti-allodynic, anti-hyperalgesic and anti-edema effects of Î9-tetrahydrocannabinol in the rat
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Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats
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Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats
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Cannabinoid Receptor Type 2 Agonist Attenuates Apoptosis by Activation of Phosphorylated CREB-Bcl-2 Pathway After Subarachnoid Hemorrhage in Rats
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Cannabinoid Receptor Type 2 Agonist Attenuates Apoptosis by Activation of Phosphorylated CREB-Bcl-2 Pathway After Subarachnoid Hemorrhage in Rats
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Peripheral neurobiologic mechanisms of antiallodynic effect of warm water immersion therapy on persistent inflammatory pain
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Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit
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Cannabinoid CB2 receptor stimulation attenuates brain edema and neurological deficits in a germinal matrix hemorrhage rat model
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Minocycline Attenuates Neonatal Germinal-Matrix-Hemorrhage-Induced Neuroinflammation and Brain Edema by Activating Cannabinoid Receptor 2
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Cannabinoid receptor 2 attenuates microglial accumulation and brain injury following germinal matrix hemorrhage via ERK dephosphorylation in vivo and in vitro
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A Cannabinoid Receptor 2 Agonist Prevents Thrombin-Induced Blood-Brain Barrier Damage via the Inhibition of Microglial Activation and Matrix Metalloproteinase Expression in Rats
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Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats
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Mustard vesicants alter expression of the endocannabinoid system in mouse skin
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Selective modulator of cannabinoid receptor type 2 reduces memory impairment and infarct size during cerebral hypoperfusion and vascular dementia
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Selective modulator of cannabinoid receptor type 2 (CB2) against biochemical alterations and brain damage in chronic cerebral hypoperfusion induced vascular dementia
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Activation of Cannabinoid Receptor 2 Attenuates Mechanical Allodynia and Neuroinflammatory Responses in a Chronic Post-Ischemic Pain Model of Complex Regional Pain Syndrome Type I in Rats
EMBRYOS/FETAL DEVELOPMENT/PLACENTAL DEVELOPMENT (44)
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The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure
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A prospective study on intrauterine cannabis exposure and fetal blood flow
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Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implications
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Modulation of the novel cannabinoid receptor â GPR55 â during rat fetoplacental development
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N-Docosahhexanoyllethanolamide promotes development of hippocampal neurons
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Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos
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Immunity and early pregnancy events: are endocannabinoids the missing link?
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TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Î9-tetrahydrocannabiorcol
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Embryonic diapause in humans: time to consider?
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Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders
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Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp) of obesity
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Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism
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Long-term consequences of perinatal fatty acid amino hydrolase inhibition
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Behavioral Responses to Acute and Sub-chronic Administration of the Synthetic Cannabinoid JWH-018 in Adult Mice Prenatally Exposed to Corticosterone
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Fatty Acid Binding Protein-4 is expressed in the mouse placental labyrinth, yet is dispensable for placental triglyceride accumulation and fetal growth
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Programming and reprogramming neural cells by (endo-) cannabinoids: from physiological rules to emerging therapies
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Gene-Specific Disruption of Endocannabinoid Receptor 1 (cnr1a) by Ethanol Probably Leads to the Development of Fetal Alcohol Spectrum Disorder (FASD) Phenotypes in Japanese Rice Fish (Oryzias latipes) Embryogenesis
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Lipid abundance in zebrafish embryos is regulated by complementary actions of the Endocannabinoid System and Retinoic Acid Pathway
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Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling
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Preferential epithelial expression of type-1 cannabinoid receptor (CB1R) in the developing canine embryo
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Endocannabinoid signaling in female reproductive events: a potential therapeutic target?
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Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta
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Long-term consequences of perinatal and adolescent cannabinoid exposure on neural and psychological processes
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Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via PGE2 and P-selectin Activity
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Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture
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Cannabinoid Receptorâ2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and PâSelectin Activity
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Use of paracetamol during pregnancy and child neurological development
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Dynamics of expression and localization of the cannabinoid system in granulosa cells during oocyte nuclear maturation
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Role of the endocannabinoid system in the mechanisms involved in the LPS-induced preterm labor
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Lipid abundance in zebrafish embryos is regulated by complementary actions of the Endocannabinoid System and Retinoic Acid Pathway
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Progesterone and anandamide in pregnancy loss
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Anandamide and Decidual Remodeling: COX-2 oxidative metabolism as a key regulator
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Epigenetic Effects of Cannabis Exposure
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The endocannabinoid 2-arachidonoylglycerol dysregulates the synthesis of proteins by the human syncytiotrophoblast
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Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice
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Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring
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Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation
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Dynamic of expression and localization of cannabinoid-degrading enzymes FAAH and MGLL in relation to CB1 during meiotic maturation of human oocytes
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The endocannabinoid system: an emergent player in human placentation
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Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor- 1
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Peripheral Blood Mononuclear Cells Infiltration Downregulates Decidual FAAH Activity in an LPS-Induced Embryo Resorption Model
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Exocannabinoids effect on in vitro bovine oocyte maturation via activation of AKT and ERK1/2
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A role for the endocannabinoid system in premature luteal regression and progesterone withdrawal in lipopolysaccharide-induced early pregnancy loss model
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Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity
ENCEPHALITIS (7)
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A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats
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Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study
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Cannabinoid receptor expression in HIV encephalitis and HIV-associated neuropathologic comorbidities
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Gadolinium-HU-308-incorporated micelles
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Prospects for cannabinoid therapies in viral encephalitis
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Prospects for cannabinoid therapies in viral encephalitis
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Anti-N-methyl-D-aspartate receptor encephalitis and drug abuse â the probable role of molecular mimicry or the overstimulation of CB receptors in a 17-year-old adolescent â case report (link to
ENCEPHALOMYELITIS/EAE (32)
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Cannabinoids and B cells: emerging targets for treating progressive multiple sclerosis
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Role of Cannabinoids in Multiple Sclerosis
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Administration of 2-arachidonoylglycerol ameliorates both acute and chronic Experimental Autoimmune Encephalomyelitis
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Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis
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Cannabinoid receptor-2-selective agonists improve recovery in experimental autoimmune encephalomyelitis
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Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB(1) receptor-mediated anti-inflammatory effects
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The biology that underpins the therapeutic potential of cannabis-based medicines for the control of spasticity in multiple sclerosis
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Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis
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Multiple sclerosis and the blood-central nervous system barrier
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Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
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Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS
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Cannabinoids: Do they have the potential to treat the symptoms of multiple sclerosis?
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R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice
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A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis
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Activating Cannabinoid Receptor 2 Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis Via Activation of Autophagy and Inhibiting NLRP3 Inflammasome
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Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis
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Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells
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A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis
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Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
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Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
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HU-446 and HU-465, derivatives of the non-psychoactive cannabinoid cannabidiol, decrease the activation of encephalitogenic T cells
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Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice
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Purified Cannabidiol, the main non-psychotropic component of Cannabis sativa, alone, counteracts neuronal apoptosis in experimental multiple sclerosis
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Neuroprotection in Experimental Autoimmune Encephalomyelitis and Progressive Multiple Sclerosis by Cannabis-Based Cannabinoids
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Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis
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Neuroprotective Effect Is Driven Through the Upregulation of CB1 Receptor in Experimental Autoimmune Encephalomyelitis
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The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Î(9)-tetrahydrocannabinol acting through CB1 receptors
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Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells
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Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis
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Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
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Development and Pharmacological Characterization of Selective Blockers of 2- Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
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WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism
ENDOMETRIOSIS (14)
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Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis
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Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations
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Endocannabinoid involvement in endometriosis
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Î9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells
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The molecular connections between the cannabinoid system and endometriosis
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Progesterone-dependent regulation of endometrial cannabinoid receptor type 1 (CB1-R) expression is disrupted in women with endometriosis and in isolated stromal cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
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β-Caryophyllene causes regression of endometrial implants in a rat model of endometriosis without affecting fertility
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Administration of micronized palmitoylethanolamide (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results
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The adjuvant use of N-palmitoylethanolamine and transpolydatin in the treatment of endometriotic pain
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Magnolol inhibits LPS-induced inflammatory response in uterine epithelial cells : magnolol inhibits LPS-induced inflammatory response
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Current Therapeutic Cannabis Controversies and Clinical Trial Design Issues
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Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis
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Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release
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The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis
EPILEPSY/SEIZURES (191)
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Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo
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Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy
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AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity
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Delta-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats
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Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans
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CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies
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Endocannabinoid system protects against cryptogenic seizures
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Redistribution of CB1 Cannabinoid Receptors in the Acute and Chronic Phases of Pilocarpine-Induced Epilepsy
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In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis
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Acetaminophen inhibits status epilepticus in cultured hippocampal neurons
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The secret âspiceâ: an undetectable toxic cause of seizure
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Convulsions Associated with the Use of a Synthetic Cannabinoid Product
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Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy
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Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice
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Protective effects of CB1 receptor agonist WIN 55.212-2 in seizure activity in the model of temporal lobe epilepsy
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L-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure
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Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures
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Neuron to Astrocyte Communication via Cannabinoid Receptors Is Necessary for Sustained Epileptiform Activity in Rat Hippocampus
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Cannabidivarin is anticonvulsant in mouse and rat
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Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
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Cannabinoid receptor 1 inhibition causes seizures during anesthesia induction in experimental sepsis
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Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain
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Cannabidiol in humans-the quest for therapeutic targets
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Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
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Epileptiform activity in the CA1 region of the hippocampus becomes refractory to attenuation by cannabinoids in part because of endogenous γ-aminobutyric acid type B receptor activity
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Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase-Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology
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Endocannabinoids via CBâ receptors act as neurogenic niche cues during cortical development
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Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
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Use of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy: Patent Application 20120004251
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Internet Highs-Seizures After Consumption of Synthetic Cannabinoids Purchased Online
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Seizure exacerbation in two patients with focal epilepsy following marijuana cessation
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Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy
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Inverse relationship of cannabimimetic (R+)WIN 55, 212 on behavior and seizure threshold during the juvenile period
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Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment resistant epilepsy
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Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder
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Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention
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Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
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Stirring the Pot With Estrogens
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Medical Marijuana Coverage Still Lost in the Legal Weeds
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Epidiolex â GW Pharmaceuticals
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Therapeutic potential of cannabinoid medicines
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Cannabis and other illicit drug use in epilepsy patients
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The role of potassium BK channels in anticonvulsant effect of cannabidiol in pentylenetetrazole and maximal electroshock models of seizure in mice
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The role of α2-adrenoceptors in the anti-convulsant effects of cannabinoids on pentylenetetrazole-induced seizure threshold in mice
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The Role of CB1-Receptors in the Proconvulsant Effect of Leptin on Penicillin-Induced Epileptiform Activity in Rats
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CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations
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Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice
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Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism
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Whole Cannabis Extracts of High Concentration Cannabidiol May Calm Seizures in Highly Refractory Pediatric Epilepsies
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The case for medical marijuana in epilepsy
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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
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Effects of WIN 55,212-2 (a non-selective cannabinoid CB1 and CB 2 receptor agonist) on the protective action of various classical antiepileptic drugs in the mouse 6 Hz psychomotor seizure model
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Modulation of pilocarpine-induced seizures by cannabinoid receptor 1
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Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity
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Physicians, Medical Marijuana, and the Law
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Phytocannabinoids and epilepsy
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Astrocytic expression of cannabinoid type 1 receptor in rat and human sclerotic hippocampi
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Presynaptic mechanisms of neuronal plasticity and their role in epilepsy
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Selected terpenoids from medicinal plants modulate endoplasmic reticulum stress in metabolic disorders
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The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments
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Cannabinoids for epilepsy
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The case for assessing cannabidiol in epilepsy
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Seizing an opportunity for the endocannabinoid system
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ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice
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Anticonvulsant Effects of N-Arachidonoyl-Serotonin, a Dual FAAH Enzyme and TRPV1 Channel Blocker, on Experimental Seizures: The Roles of Cannabinoid CB1 Receptors and TRPV1 Channels
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Disease-Modifying Effects of RHC80267 and JZL184 in a Pilocarpine Mouse Model of Temporal Lobe Epilepsy
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Cannabidiol: Promise and Pitfalls
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Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues
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The Comprehensive Report on the Cannabis Extract Movement and the Use of Cannabis Extracts to Treat Diseases
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A âspicyâ encephalopathy: synthetic cannabinoids as cause of encephalopathy and seizure
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EFFICACY AND SAFETY OF EPIDIOLEX (CANNABIDIOL) IN CHILDREN AND YOUNG ADULTS WITH TREATMENT-RESISTANT EPILEPSY: INITIAL DATA FROM AN EXPANDED ACCESS PROGRAM
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âCrazy Monkeyâ Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid
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Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se
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Cannabinoids for epilepsy: is marijuana an effective treatment for epilepsy?
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The non-psychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability
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Pentylenetetrazol-induced seizure-like behavior and neural hyperactivity in the medicinal leech
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Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting
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Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal sub-population-specific effects on epileptogenesis in the kindling paradigm
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Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues
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The interaction between ghrelin and cannabinoid systems in penicillin-induced epilepti-form activity in rats
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Cannabis, cannabidiol, and epilepsy â From receptors to clinical response
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Influence of WIN 55,212-2 on the anticonvulsant and acute neurotoxic potential of clobazam and lacosamide in the maximal electroshock-induced seizure model and chimney test in mice
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Role of CB2 receptors and cGMP pathway on the cannabinoid-dependent antiepileptic effects in an in vivo model of partial epilepsy
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Circumventing seizure activity in a series of G protein coupled receptor 119 (GPR119) agonists
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Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2
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Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats
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Changes and overlapping distribution in the expression of CB1/OX1-GPCRs in rat hippocampus by kainic acid-induced status epilepticus
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Medical marijuana and children
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Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users
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THE EFFECT OF EPIDIOLEX (CANNABIDIOL) ON SERUM LEVELS OF CONCOMITANT ANTI-EPILEPTIC DRUGS IN CHILDREN AND YOUNG ADULTS WITH TREATMENT-RESISTANT EPILEPSY IN AN EXPANDED ACCESS PROGRAM
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RESOLUTION OF SEIZURES AND NORMALIZATION OF EEG AFTER INITIATION OF CBD IN A PATIENT WITH DOOSE SYNDROME
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Augmented Inhibition from Cannabinoid-Sensitive Interneurons Diminishes CA1 Output after Traumatic Brain Injury
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Muscarinic M1 receptor and cannabinoid CB1 receptor do not modulate paraoxon induced seizures
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Fatty Acid Binding Proteins (FABPs) are Intracellular Carriers for Î9-Tetrahydro-cannabinol (THC) and Cannabidiol (CBD)
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Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine
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Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms
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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
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Interaction between Cannabinoid Compounds and Capsazepine in Protection against Acute Pentylenetetrazole-induced Seizure in Mice
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Phytocannabinoids and epilepsy
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Cannabinoids and Epilepsy
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Impaired 2-AG signaling in hippocampal glutamatergic neurons: aggravation of anxiety-like behavior and unaltered seizure susceptibility
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Cannabinoids: is there a potential treatment role in epilepsy?
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Investigational new drugs for focal epilepsy
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Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks
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TRPV1 Channel: A Potential Drug Target for Treating Epilepsy
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Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
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Homer Protein-Metabotropic Glutamate Receptor Binding Regulates Endocannabinoid Signaling and Affects Hyperexcitability in a Mouse Model of Fragile X Syndrome
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The basolateral amygdala γ-aminobutyric acidergic system in health and disease
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Enhancement of endocannabinoid signalling protects against cocaine-induced neurotoxicity
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Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy
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Marijuana: A Time-Honored but Untested Treatment for Epilepsy
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Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
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Neuroprotective effects of trans-caryophyllene against kainic Acid induced seizure activity and oxidative stress in mice
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Effects of WIN 55,212-2 (a synthetic cannabinoid CB1 and CB2 receptor agonist) on the anticonvulsant activity of various novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice
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Options for pharmacoresistant epilepsy in children: when medications donât work
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A Common Source Outbreak of Severe Delirium Associated with Exposure to the Novel Synthetic Cannabinoid ADB-PINACA
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Attenuation of kainic acid-induced status epilepticus by inhibition of endocannabinoid transport and degradation in guinea pigs
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Marijuana: A Time-Honored but Untested Treatment for Epilepsy
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Inhibition of monoacylglycerol lipase mediates a cannabinoid 1-receptor dependent delay of kindling progression in mice
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Withdrawal Seizures Seen In the Setting of Synthetic Cannabinoid Abuse
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Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy
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The role of cannabinoids and leptin in neurological diseases
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Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report
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Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy
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Influence of arachidonyl-2â²-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide and pregabalin in the maximal electroshock-induced seizure model and chimney test in mice
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Long-term disease-modifying effect of the endocannabinoid agonist WIN55,212-2 in a rat model of audiogenic epilepsy
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Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox-Gastaut syndrome
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JWH-018 impairs sensorimotor functions in mice
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Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: Study on electrophysiological and behavioral models of temporal lobe epilepsy in the rat
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Changes over time of cannabinoid receptor 1 in hippocampus of status epilepticus rats
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ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs
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Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release
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Marijuana Use in Epilepsy: The Myth and the Reality
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Issues and promise in clinical studies of botanicals with anticonvulsant potential
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Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11
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Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors
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Cannabis and Endocannabinoid Signaling in Epilepsy
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Pentylenetetrazol-induced seizure-like behavior and neural hyperactivity in the medicinal leech
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Cannabidiol as potential treatment in refractory pediatric epilepsy
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The effects of adolescent cannabinoid exposure on seizure susceptibility and lethality in adult male rats
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Influence of arachidonylâ2â²âchloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute sideâeffect potentials of clobazam, lacosamide, and pregabalin in the maximal electroshockâinduced seizure model and chimney test in mice
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Convulsant effects of high efficacy synthetic cannabinoid JWH-018 in mice
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The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole induced seizure severity in Wistar rats
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The Pharmacological Basis of Cannabis Therapy for Epilepsy
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Cannabinoids for pediatric epilepsy? Up in smoke or real science?
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Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling
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Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome
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ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice
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CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience
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Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center
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Synthetic cannabinoids revealing adrenoleukodystrophy
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Is the medical use of cannabis a therapeutic option for children?
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Fatty Acid Binding Proteins are Intracellular Carriers for THC and CBD
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Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
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Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures
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Turning Up the Heat on Endocannabinoid Signaling
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Î9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol
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Medical Marijuana for Epilepsy?
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Investigational new drugs for focal epilepsy
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Cannabis and Cannabinoids
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Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure
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Adverse effects after the use of JWH-210 â a case series from the EU Spice II plus project
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Effect of JWH-250, JWH-073 and their interaction on âtetradâ, sensorimotor, neurological and neurochemical responses in mice
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Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy
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Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures
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Plant-Derived and Endogenous Cannabinoids in Epilepsy
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Involvement of TRPV1 channels in the activity of the cannabinoid WIN 55,212-2 in an acute rat model of temporal lobe epilepsy
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Cannabidiol and epilepsy: rationale and therapeutic potential
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LACTIC ACIDOSIS: A RARE MANIFESTATION OF SYNTHETIC MARIJUANA INTOXICATION
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MEDICAL CANNABIS
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CB1 Receptor Antagonism Prevents Long-Term Hyperexcitability after Head Injury by of Dynorphin-KOR System and mGluR5 in Rat Hippocampus
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Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol
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Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents
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Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation
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The cannabinoid receptor agonist WIN55.212 reduces consequences of status epilepticus in rats
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Marijuana use in adults admitted to a Canadian epilepsy monitoring unit
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From cannabis to cannabidiol to treat epilepsy, where are we?
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Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl- 2â²-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice
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Effects of Marijuana on ictal and interictal EEG activity in idiopathic generalized epilepsy
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Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl- 2â²-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice
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Endogenous cannabinoid system alterations and their role in epileptogenesis after brain injury in rat
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Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry
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Cannabis and epilepsy: An ancient treatment returns to the fore
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Pharmacology of cannabinoids in the treatment of epilepsy
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Using Medical Marijuana to Stop Childhood Seizures
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Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients
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Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences (link to
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Historical perspective on the medical use of cannabis for epilepsy: Ancient times to the 1980s
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Neuroimaging studies towards understanding the central effects of pharmacological cannabis products on patients with epilepsy
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Social factors in marijuana use for medical and recreational purposes
ESSENTIAL TREMOR (3)
EXERCISE and the ENDOCANNABINOID SYSTEM (42)
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Endocannabinoids and voluntary activity in mice: runnerâs high and long-term consequences in emotional behaviors
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Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults
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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise
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High-performance sport, marijuana, and cannabimimetics
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Effects of exercise stress on the endocannabinoid system in humans under field conditions
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Naloxone and rimonabant reduce the reinforcing properties of exercise in rats
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Intense exercise increases circulating endocannabinoid and BDNF levels in humans-Possible implications for reward and depression
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Wired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the ârunnerâs highâ
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The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity
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Exercise-induced endocannabinoid signaling is modulated by intensity
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Ventral Tegmental Area Cannabinoid Type-1 Receptors Control Voluntary Exercise Performance
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Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex
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The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance
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A role for the endocannabinoid system in exercise-induced spatial memory enhancement in mice
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Exercise Addiction- Diagnosis, Bio-Psychological Mechanisms and Treatment Issues
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Exercise increases plasma THC concentrations in regular cannabis users
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The endocannabinoid system mediates aerobic exercise-induced antinociception in rats
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Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System
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Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament
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Can Physical Exercise or Food Deprivation Cause Release of Fat-Stored Cannabinoids?
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CB1 receptor affects cortical plasticity and response to physiotherapy in multiple sclerosis
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Acute Resistance Exercise Induces Antinociception by Activation of the Endocannabinoid System in Rats
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Mechanisms of Exercise-Induced Hypoalgesia
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Molecular Basis for the Improvement in Muscle Metaboreflex and Mechanoreflex Control in Exercise-Trained Humans with Chronic Heart Failure
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Effects of Two Different Specific Neck Exercise Interventions on Palmitoylethanol-amide and Stearoylethanolamide Concentrations in the Interstitium of the Trapezius Muscle in Women with Chronic Neck Shoulder Pain
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Modulation of early stress-induced neurobiological changes: a review of behavioural and pharmacological interventions in animal models
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Physical activity and the endocannabinoid system: an overview
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Physical activity and cannabis cessation
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Fasting and exercise increase plasma cannabinoid levels in THC pre-treated rats: an examination of behavioural consequences
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Effect of dronabinol therapy on physical activity in anorexia nervosa: a randomised, controlled trial
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The fatty acid amide hydrolase in lymphocytes from sedentary and active subjects
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A runnerâs high depends on cannabinoid receptors in mice
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Cannabinoid Receptor 1 and Acute Resistance Exercise â In vivo and In vitro Studies in Human Skeletal Muscle
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Deletion of G-protein coupled receptor 55 promotes obesity by reducing physical activity
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Cannabis and Exercise Science: A Commentary on Existing Studies and Suggestions for Future Directions
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3 Runnerâs high linked to cannabinoid receptors in mice
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Neuromodulation of Aerobic ExerciseâA Review
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Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans
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Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity
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Exercise deprivation increases negative mood in exercise-addicted subjects and modifies their biochemical markers
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Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids
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Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes