Medisinsk forskning på cannabis
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NARCOLEPSY (1)
NAUSEA (95)
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Regulation of nausea and vomiting by cannabinoids
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Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
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Motion Sickness, Stress and the Endocannabinoid System
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Cannabinoid-Induced Hyperemesis: A ConundrumâFrom Clinical Recognition to Basic Science Mechanisms
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Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting
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Pharmacology and toxicology of Cannabis derivatives and endocannabinoid agonists
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The abuse potential of the synthetic cannabinoid nabilone
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Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Auto-receptors in the Dorsal Raphe Nucleus
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Regulation of nausea and vomiting by cannabinoids
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The intersection between cannabis and cancer in the United States
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Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea?
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Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
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Medical cannabis: the opportunity versus the temptation
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Medical Marijuana: Clearing Away the Smoke
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Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
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The anti-nausea effects of CB(1) agonists are mediated by an action at the visceral insular cortex
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The Therapeutic Potential of Cannabis and Cannabinoids
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Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids
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Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats
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Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting
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Effects of parabolic flight and spaceflight on the endocannabinoid system in humans
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Effects of dronabinol on morphine-induced dopamine-related behavioral effects in animals
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Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation
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Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour) in rats
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Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Î9 -tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats
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Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus)
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Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
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Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus
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The Medical Necessity for Medicinal Cannabis: Prospective, Observational Study Evaluating the Treatment in Cancer Patients on Supportive or Palliative Care
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Dronabinol Treatment of Refractory Nausea and Vomiting Related to Peritoneal Carcinomatosis
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Therapeutic potential of cannabinoid medicines
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Additive antiemetic efficacy of 9-THC with vanilloid TRPV1 receptor agonists in the least shrew (Cryptotis parva)
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Additive antiemetic efficacy of low-doses of the cannabinoid CB1/2 receptor agonist Î9-THC with ultralow-doses of the vanilloid TRPV1 receptor agonist resiniferatoxin in the least shrew (Cryptotis parva)
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2-arachidonoylglycerol interferes with lithium-induced vomiting in the house musk shrew, Suncus murinus
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Suppression of lithium chloride-induced conditioned gaping (a model of nausea-induced behaviour) in rats (using the taste reactivity test) with metoclopramide is enhanced by cannabidiolic acid
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Nabilone for Non-chemotherapy Associated Nausea and Weight Loss due to Medical Conditions: A Review of the Clinical Effectiveness and Guidelines [Internet]
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Medical marijuana for cancer
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Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not âhigherâ
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Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not âhigherâ
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Medical marijuana: more questions than answers
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Medical marijuana: more questions than answers
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K2-Not the Spice of Life, Synthetic Cannabinoids and ST Elevation Myocardial Infarction: A Case Report
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Dexamethasone alleviates motion sickness in rats in part by enhancing the endo-cannabinoid system
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A comparison of cannabidiolic acid with other treatments for anticipatory nausea using a rat model of contextually elicited conditioned gaping
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Meta-analysis of adjunctive non-NK1 receptor antagonist medications for the control of acute and delayed chemotherapy-induced nausea and vomiting
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Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus
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Therapeutic Potential of Cannabinoids in Counteracting Chemotherapy-induced Adverse Effects: An Exploratory Review
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Therapeutic Potential of Cannabinoids in Counteracting Chemotherapy-induced Adverse Effects: An Exploratory Review
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Potential applications of marijuana and cannabinoids in medicine
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The successful use of dronabinol for failure to thrive secondary to intestinal dysmotility
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Cannabis in cancer care
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Cannabinoid hyperemesis syndrome: Marijuana is both antiemetic and proemetic
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Cannabinoids for Medical Use A Systematic Review and Meta-analysis
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Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
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Novel associations between FAAH genetic variants and postoperative central opioid related adverse effects
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Medical Marijuana: Is the Cart Before the Horse?
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Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy
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Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy
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Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2)
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Intra-visceral insular cortex 2-arachidonoylglycerol, but not N arachidonoylethanolamide, suppresses acute nausea-induced conditioned gaping in rats
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The role of cannabinoids in regulation of nausea and vomiting, and visceral pain
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Cannabinoids suppress acute and anticipatory nausea in pre-clinical rat models of conditioned gaping
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Synergy between cannabidiol, cannabidiolic acid, and Îâ¹-tetrahydrocannabinol in the regulation of emesis in the Suncus murinus (house musk shrew)
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Interference with acute nausea and anticipatory nausea in rats by fatty acid amide hydrolase (FAAH) inhibition through a PPARα and CB1 receptor mechanism, respectively: a double dissociation
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Cannabis â therapy for the future?
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Effect of combined doses of Î9-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping
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Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea
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Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex
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Controlled release tablet formulation containing natural δ9 tetrahydrocannabinol
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Endocannabinoid Mechanisms Influencing Nausea
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Intravenous Delta-9-Tetrahydrocannabinol to Prevent Postoperative Nausea and Vomiting: A Randomized Controlled Trial
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Cannabis and cancer: toward a new understanding
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Integrating cannabis into clinical cancer care
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Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics
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The Gut-Itch Connection
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The involvement of TRPV1 in emesis and anti-emesis
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A userâs guide to cannabinoid therapies in oncology
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Cannabis and Cannabinoids (PDQ®)Health Professional Version
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Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
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Using Medical Cannabis in an Oncology Practice
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Using Medical Cannabis in an Oncology Practice
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Cannabis and Cannabinoids
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Medical use of cannabis products : Lessons to be learned from Israel and Canada
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Adverse effects after the use of JWH-210 â a case series from the EU Spice II plus project
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Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea
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Efficacy, tolerability, and safety of cannabinoids in gastroenterology : A systematic review
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Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model
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A comparison of novel, selective fatty acid amide hydrolase (FAAH), monoacyglycerol lipase (MAGL) or dual FAAH/MAGL inhibitors to suppress acute and anticipatory nausea in rat models
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Cannabinoid 2 (CB2) receptor agonism reduces lithium chloride-induced vomiting in Suncus murinus and nausea-induced conditioned gaping in rats
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Cannabinoids for Symptom Management and Cancer Therapy: The Evidence
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Effect of combined oral doses of Î9-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea in rat models
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Hypophosphatemia in Users of Cannabis
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Novel Treatments for Cyclic Vomiting Syndrome: Beyond Ondansetron and Amitriptyline
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Role of cannabis in digestive disorders
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Expertsâ Perspectives on the Role of Medical Marijuana in Oncology: a semi-structured interview study
NEOINTIMA (4)
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Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies
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Cannabinoid receptor CB2 protects against balloon-induced neointima formation
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Endogenous cannabinoid receptor CB1 activation promotes vascular smooth muscle cell proliferation and neointima formation
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Magnolol inhibits migration of vascular smooth muscle cells via cytoskeletal remodeling pathway to attenuate neointima formation
NEUROGENESIS (35)
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Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis
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Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
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Converging action of alcohol consumption and cannabinoid receptor activation on adult hippocampal neurogenesis
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CB1 receptor deficiency decreases wheel-running activity: consequences on emotional behaviours and hippocampal neurogenesis
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Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
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CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
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EFFECT OF CANNABIS SATIVA ALCOHOLIC EXTRACT ON HIPPOCAMPUS NEURONAL DENSITY IN RATS
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Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?
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Endocannabinoids via CBâ receptors act as neurogenic niche cues during cortical development
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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
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Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?
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Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures
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The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
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Neuroimmmune interactions of cannabinoids in neurogenesis: focus on interleukin-1β (IL-1β) signalling
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CB2 cannabinoid agonist enhanced neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis
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High hopes for CB(2) receptors in neurogenesis
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The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis
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Impaired Neurogenesis by HIV-1-Gp120 is Rescued by genetic deletion of Fatty Acid Amide Hydrolase Enzyme
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Impaired Neurogenesis by HIV-1-Gp120 is Rescued by genetic deletion of Fatty Acid Amide Hydrolase Enzyme
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Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion
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Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity
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Potential Therapeutical Contributions of the Endocannabinoid System towards Aging and Alzheimerâs Disease
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Programming and reprogramming neural cells by (endo-) cannabinoids: from physiological rules to emerging therapies
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Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
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The role of cannabinoids in adult neurogenesis
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Influence of single and repeated cannabidiol administration on emotional behavior and markers of cell proliferation and neurogenesis in non-stressed mice
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ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs
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Ultra-low doses of tetrahydrocannabinol contribute to the survival of newly-born cells in the dentate gyrus of adult rats
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Cannabidiol, neuroprotection and neuropsychiatric disorders
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Functional effects of cannabinoids during dopaminergic specification of human neural precursors derived from induced pluripotent stem cells
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Distinctive effects of eicosapentaenoic and docosahexaenoic acids in regulating neural stem cell fate are mediated via endocannabinoid signalling pathways
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Cannabinoid receptor signaling induces proliferation but not neurogenesis in the mouse olfactory epithelium
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Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
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Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke
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Cannabidiol Activates Neuronal Precursor Genes in Human Gingival Mesenchymal Stromal Cells
NEUROMYELITIS OPTICA/DEVICAâS DISEASE (1)
NEURONS/BRAIN CELLS (445)
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Cyclooxygenase-2 Mediates Anandamide Metabolism in the Mouse Brain
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Cannabinoids Excite Circadian Clock Neurons
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Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis
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Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus
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AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity
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Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior
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CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT / glycogen synthase kinase-3beta/beta-catenin signaling
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Converging action of alcohol consumption and cannabinoid receptor activation on adult hippocampal neurogenesis
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Endocannabinoids Prevent β-Amyloid-mediated Lysosomal Destabilization in Cultured Neurons
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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
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Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation
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Endocannabinoids: Going retro with DAGLα
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Effects of caffeine on striatal neurotransmission: focus on cannabinoid CB1 receptors
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Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain
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PP-014 Control of receptor expression in vagal afferent neurons by activation of cannabinoid 1 receptors
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Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mito-chondria upon paraquat exposure
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Dopamine modulation of excitatory currents in the striatum is dictated by the expression of D1 or D2 receptors and modified by endocannabinoids
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Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
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A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development
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A catalytically silent FAAH-1 variant drives anandamide transport in neurons
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Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior
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Dual inhibition of alpha/beta hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons
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Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
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CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity
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Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss
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Cannabinoid receptor expression in HIV encephalitis and HIV-associated neuro-pathologic comorbidities
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Cannabinoid receptor-mediated regulation of neuronal activity in the main olfactory bulb
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Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction
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CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
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History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability
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HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions
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Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation
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Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults
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The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors
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Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults
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Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress
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The major central endocannabinoid directly acts at GABA(A) receptors
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N-Docosahhexanoyllethanolamide promotes development of hippocampal neurons
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Alterations in Corticolimbic Dendritic Morphology and Emotional Behavior in Cannabinoid CB1 ReceptorâDeficient Mice Parallel the Effects of Chronic Stress
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Synaptic plasticity: A new partnership
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History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability
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The Effect of Hypoxia on G Protein Coupled (CB1) Receptor Gene Expression in Cortical B50 Neurons in Culture
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The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro
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α-Tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus
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Plasticity in vagal afferent neurones during feeding and fasting: mechanisms and significance
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Effects of synthetic cannabinoids on electroencephalogram power spectra in rats
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Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions
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Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. Figure 1: n-3/n-6 PUFA dietary imbalance alters PUFAs level in mouse brain
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Î(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner
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Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy induced painful neuropathy
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Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury
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EFFECT OF CANNABIS SATIVA ALCOHOLIC EXTRACT ON HIPPOCAMPUS NEURONAL DENSITY IN RATS
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EFFECT OF AQUATIC EXTRACT OFCANNABIS SATIVA LEAVES ON DEGENERATION OF ALPHA MOTONEURONS IN SPINAL CORD AFTER SCIATIC NERVE COMPRESSION IN RATS
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Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors
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Endocannabinoids in nervous system health and disease: the big picture in a nutshell
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Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging
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Type-1 Cannabinoid Receptor Signaling in Neuronal Development
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Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system
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Synaptic Targets of Î9-Tetrahydrocannabinol in the Central Nervous System
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Endocannabinoids and the processing of value-related signals
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Neuron to Astrocyte Communication via Cannabinoid Receptors Is Necessary for Sustained Epileptiform Activity in Rat Hippocampus
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Pathological plasticity in fragile X syndrome
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Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α
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Review article: The endocannabinoid system in normal and pathological brain ageing
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Excitability of prefrontal cortical pyramidal neurons is modulated by activation of 98 intracellular type-2 cannabinoid receptors
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Intrinsic Up-Regulation of 2-AG Favors an Area Specific Neuronal Survival in Different In Vitro Models of Neuronal Damage
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Functional diversity on synaptic plasticity mediated by endocannabinoids
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Endocannabinoids via CBâ receptors act as neurogenic niche cues during cortical development
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The CB(2)-preferring agonist JWH015 also potently and efficaciously activates CB(1) in autaptic hippocampal neurons
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Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids
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The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis
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Multiple functions of endocannabinoid signaling in the brain
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Psychopharmacology of the endocannabinoids: far beyond anandamide
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Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling
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Pharmacological manipulation of cannabinoid neurotransmission reduces neuro-inflammation associated with normal aging
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A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord
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Mitochondrial CB(1) receptors regulate neuronal energy metabolism
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Effects of cannabinoids Î(9)-tetrahydrocannabinol, Î(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures
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Cannabinoid modulation of midbrain urocortin 1 neurones during acute and chronic stress
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Manipulating brain connectivity with δ(9)-tetrahydrocannabinol: A pharmacological resting state FMRI study
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Cannabinoid CB(1) receptor in the modulation of stress coping behaviour in mice: the role of serotonin and different forebrain neuronal subpopulations
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The role of endocannabinoids in pain modulation
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Type-1 (CB(1)) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells
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Orexin neurons use endocannabinoids to break obesity-induced inhibition
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Signaling Pathways Involved in Striatal Synaptic Plasticity are Sensitive to Temporal Pattern and Exhibit Spatial Specificity
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A biophysical model of endocannabinoid-mediated short term depression in hippocampal inhibition
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The endocannabinoid system, cannabinoids, and pain
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Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures
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N-arachidonoyl-L-serine (AraS) possesses proneurogenic properties in vitro and in vivo after traumatic brain injury
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Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic-ischemic brain injury
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HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity
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Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons
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Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neuro-transmitter release at central synapses
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Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats
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Association between a genetic variant of type-1 cannabinoid receptor and inflammatory neurodegeneration in multiple sclerosis
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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
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Food for thought: hormonal, experiential, and neural influences on feeding and obesity
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Temporal changes of CB1 cannabinoid receptor in the basal ganglia as a possible structure-specific plasticity process in 6-OHDA lesioned rats
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Neuroprotective effects of Cannabis sativa leaves extracts on α-Motoneurons density after sciatic nerve injury in rats
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Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus
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Diacylglycerol Lipaseα (DAGLα) and DAGLβ Cooperatively Regulate the Production of 2-Arachidonoyl Glycerol in Autaptic Hippocampal Neurons
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CB2 Receptor Agonists Protect Human Dopaminergic Neurons against Damage from HIV-1 gp120
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Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes
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Sex-specific tonic 2-arachidonoylglycerol signaling at inhibitory inputs onto dopamine neurons of Lister Hooded rats
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Insulin induces long-term depression of VTA dopamine neurons via endocannabinoids
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Rapid Glucocorticoid-Induced Activation of TRP and CB1 Receptors Causes Biphasic Modulation of Glutamate Release in Gastric-Related Hypothalamic Preautonomic Neurons
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Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface
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Therapeutic Opportunities through the Modulation of Endocannabinoid Transport
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CB2 cannabinoid agonist enhanced neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis
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CB1 Cannabinoid Receptors Promote Maximal FAK Catalytic Activity By Stimulating Cooperative Signaling Between Receptor Tyrosine Kinases and Integrins in Neuronal Cells
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Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde synaptic suppression: evidence for on-demand biosynthesis of 2-arachidonoylglycerol
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Optogenetic identification of an intrinsic cholinergically driven inhibitory oscillator sensitive to cannabinoids and opioids in hippocampal CA1
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Induction of Endocannabinoid Levels in Juvenile Rat Brain Following Developmental Chlorpyrifos Exposure
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High fat diet and body weight have different effects on cannabinoid CB1 receptor expression in rat nodose ganglia
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Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
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The role of endocannabinoids in pain modulation
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The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects
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2-AG into the lateral hypothalamus increases REM sleep and cFos expression in melanin concentrating hormone neurons in rats
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The satiety signal oleoylethanolamide stimulates oxytocin neurosecretion from rat hypothalamic neurons
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Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons
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Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death
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Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta
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Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors
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Î(9)-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18
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Presynaptic mechanisms of neuronal plasticity and their role in epilepsy
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Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity
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Cannabinoid, melanocortin and opioid receptor expression on DRD1 and DRD2 sub-populations in rat striatum
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Anandamide Protects HT22 Cells Exposed to Hydrogen Peroxide by Inhibiting CB1 Receptor-Mediated Type 2 NADPH Oxidase
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Regulatory effects of anandamide on intracellular Ca(2+) concentration increase in trigeminal ganglion neurons
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Endocannabinoid-dependent modulation of phasic dopamine signaling encodes external and internal reward-predictive cues
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Cannabinoid receptors contribute to astroglial Ca2+-signalling and control of synaptic plasticity in the neocortex
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Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
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High hopes for CB(2) receptors in neurogenesis
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Input- and Cell-Type-Specific Endocannabinoid-Dependent LTD in the Striatum
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Individual differences in response to positive and negative stimuli: endocannabinoidbased insight on approach and avoidance behaviors
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CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin
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CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model
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β-Amyloid Inhibits E-S Potentiation through Suppression of Cannabinoid Receptor 1-Dependent Synaptic Disinhibition
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Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors
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Î(9)-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18
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The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP / Gp120 transgenic mice displaying deficits in neurogenesis
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Fatty Acid-binding Protein 5 (FABP5) Regulates Cognitive Function Both by Decreasing Anandamide Levels and by Activating the Nuclear Receptor Peroxisome Proliferatoractivated Receptor β/δ (PPARβ/δ) in the Brain
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Multiple Mechanistically Distinct Modes of Endocannabinoid Mobilization at Central Amygdala Glutamatergic Synapses
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Advances in the management of multiple sclerosis spasticity: multiple sclerosis spasticity nervous pathways
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Control of synaptic function by endocannabinoid-mediated retrograde signaling
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Effects of pubertal cannabinoid administration on attentional set-shifting and dopaminergic hyper-responsivity in a developmental disruption model of schizophrenia
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Hypoximimetic activity of N-acyl-dopamines. N-arachidonoyl-dopamine stabilizes HIF-1α protein through a SIAH2-dependent pathway
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Astrocytes in endocannabinoid signalling
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Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats
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Cannabinoid Receptor Type 2 Agonist Attenuates Apoptosis by Activation of Phosphorylated CREB-Bcl-2 Pathway After Subarachnoid Hemorrhage in Rats
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Molecular Basis for the Improvement in Muscle Metaboreflex and Mechanoreflex Control in Exercise-Trained Humans with Chronic Heart Failure
-
Role of corticosterone in the murine enteric nervous system during fasting
-
Impaired Neurogenesis by HIV-1-Gp120 is Rescued by genetic deletion of Fatty Acid Amide Hydrolase Enzyme
-
Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice
-
Morphological and Behavioural Evidence for Impaired Prefrontal Cortical Function in Female CB1 Receptor Deficient Mice
-
Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey
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Activation of CB1 inhibits NGF-induced sensitization of TRPV1 in adult mouse afferent neurons
-
Developmental Increase in Hippocampal Endocannabinoid Mobilization: Role of Metabotropic Glutamate Receptor Subtype 5 and Phospholipase C
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Type 1 Cannabinoid Receptor Ligands Display Functional Selectivity in a Cell Culture Model of Striatal Medium Spiny Projection Neurons
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Hippocampal Cannabinoid Transmission Modulates Dopamine Neuron Activity: Impact on Rewarding Memory Formation and Social Interaction
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Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
-
Normal aging in rats and pathological aging in human Alzheimer disease decrease FAAH activity: Modulation by cannabinoid agonists
-
Cannabinoid Type 1 (CB1) Receptors on Sim1-Expressing Neurons Regulate Energy Expenditure in Male Mice
-
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors
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Multifractal analysis of information processing in hippocampal neural ensembles during working memory under Î9-tetrahydrocannabinol administration
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Endocannabinoids in Synaptic Plasticity and Neuroprotection
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Chronic activation of CB2 cannabinoid receptors in the hippocampus increases excitatory synaptic transmission
-
Cannabinoid modulation of drug reward and the implications of marijuana legalization
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The Neurobiology of Cancer Pain
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Effects of cannabidiol in the treatment of patients with Parkinsonâs disease: An exploratory double-blind trial
-
Programming and reprogramming neural cells by (endo-) cannabinoids: from physiological rules to emerging therapies
-
Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion
-
Anandamide in primary sensory neurons: too much of a good thing?
-
Trans-Caryophyllene Suppresses Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia
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Endocannabinoid 2-Arachidonylglycerol Protects Primary Cultured Neurons Against LPS-Induced Impairments in Rat Caudate Nucleus
-
Cellular approaches to the interaction between cannabinoid receptor ligands and nicotinic acetylcholine receptors
-
Mechanisms of synaptic dysfunction and excitotoxicity in Huntingtonâs disease
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Endocannabinoid-mediated retrograde modulation of synaptic transmission
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Inhibition of Peripheral Fatty Acid Amide Hydrolase Depresses Activities of Bladder Mechanosensitive Nerve Fibers of the Rat
-
Effect of N-Arachidonoyl Dopamine on Activity of Neuronal Network in Primary Hippo-campus Culture upon Hypoxia Modelling
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Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury
-
Endocannabinoid signaling modulates neurons of the pedunculopontine nucleus (PPN) via astrocytes
-
Cannabinoid Receptor-2 and HIV-Associated Neurocognitive Disorders
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Cannabinoid receptor intracellular signalling: The long journey from binding sites to biological effects
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The Neurobiology of Cancer Pain
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The interaction between serotonergic and cannabinoidergic modulations involved in the fear extinction
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Descending modulation of pain: the GABA disinhibition hypothesis of analgesia
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Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntingtonâs disease
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Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal sub-population-specific effects on epileptogenesis in the kindling paradigm
-
Cannabinoid-mediated short-term plasticity in hippocampus
-
Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus
-
Cannabinoid-induced changes in respiration of brain mitochondria
-
Inhibition of endocannabinoid neuronal uptake and hydrolysis as strategies for developing anxiolytic drugs
-
Differences in receptor binding affinity of several phytocannabinoids does not explain their effects on neural cell cultures
-
Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats
-
Cannabinoid receptor agonists reduce the short-term mitochondrial dysfunction and oxidative stress linked to excitotoxicity in the rat brain
-
Identification of CB2 receptors in human nigral neurons that degenerate in Parkinsonâs disease
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Cerebellar Endocannabinoids: Retrograde Signaling from Purkinje Cells
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Protective effects of cannabidiol against hippocampal cell death and cognitive impairment induced by bilateral common carotid artery occlusion in mice
-
Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine
-
Endocannabinoid Modulation of Synaptic Inputs to Magnocellular Neurons
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Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
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Augmented Inhibition from Cannabinoid-Sensitive Interneurons Diminishes CA1 Output after Traumatic Brain Injury
-
Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination in vivo
-
Cocaine-induced endocannabinoid release modulates behavioral and neurochemical sensitization in mice
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Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review
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Genetic Dissection of Behavioural and Autonomic Effects of Î9-Tetrahydrocannabinol in Mice
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The Combined Inhibitory Effect of the Adenosine A1 and Cannabinoid CB1 Receptors on cAMP Accumulation in the Hippocampus Is Additive and Independent of A1 Receptor Desensitization
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Drugs of Abuse in HIV infection and neurotoxicity
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Negative Regulation of Leptin-induced ROS Formation by CB1 Receptor Activation in Hypothalamic Neurons
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WIN 55,212-2, Agonist of Cannabinoid Receptors, Prevents Amyloid β1-42 Effects on Astrocytes in Primary Culture
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Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS
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Promising cannabinoid-based therapies for Parkinsonâs disease: motor symptoms to neuroprotection
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Role for Endogenous BDNF in Endocannabinoid-Mediated Long-Term Depression at Neocortical Inhibitory Synapses
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Sex-dependent vulnerability to Cannabis abuse in adolescence
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Involvement of GluR2 up-regulation in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptor in mice
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Effects of high-fructose diets on central appetite signaling and cognitive function
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Rapid Non-Genomic Glucocorticoid Actions in Male Mouse Hypothalamic Neuroendocrine Cells Are Dependent on the Nuclear Glucocorticoid Receptor
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The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K / Akt / mTORC1 / BDNF pathway
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Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation
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Palmitoylethanolamide Inhibits Glutamate Release in Rat Cerebrocortical Nerve Terminals
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Tonic endocannabinoid-mediated modulation of GABA release is independent of the CB1 content of axon terminals
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Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures
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Hypothalamic POMC neurons promote cannabinoid-induced feeding
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Homeostatic regulation of brain functions by endocannabinoid signaling
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Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action
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Impaired 2-AG signaling in hippocampal glutamatergic neurons: aggravation of anxietylike behavior and unaltered seizure susceptibility
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Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release
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Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments
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Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
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The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons
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Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling
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Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control
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Fine-tuning of synaptic upscaling at excitatory synapses by endocannabinoid signaling is mediated via the CB1 receptor
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Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling
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Endocannabinoid signaling mediates oxytocin-driven social reward
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Ventral tegmental area dopamine and GABA neurons: Physiological properties and expression of mRNA for endocannabinoid biosynthetic elements
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Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks
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Hypothalamic control of brown adipose tissue thermogenesis
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CB1 cannabinoid receptor enrichment in the ependymal region of the adult human spinal cord
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Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks
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CB1 cannabinoid receptor enrichment in the ependymal region of the adult human spinal cord
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Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex
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Cannabinoid receptor activation in the juvenile rat brain results in rapid biomechanical alterations: Neurovascular mechanism as a putative confounding factor
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cnrip1 is a regulator of eye and neural development in Xenopus laevis
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To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making
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Neural correlates of cannabidiol and Î9-tetrahydrocannabinol interactions in mice: implications for medical cannabis
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Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinsonâs disease
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Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-Induced Neuroinflammation
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Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area
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Cellular Mechanisms of Action of Drug Abuse on Olfactory Neurons
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Interactions between ethanol and the endocannabinoid system at GABAergic synapses on basolateral amygdala principal neurons
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Corticotropin-Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety
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Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions
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VGluT3-Expressing CCK-Positive Basket Cells Construct Invaginating Synapses Enriched with Endocannabinoid Signaling Proteins in Particular Cortical and Cortex-Like Amygdaloid Regions of Mouse Brains
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Cannabinoid CB1 Receptor Calibrates Excitatory Synaptic Balance in the Mouse Hippocampus
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Role of dopamine type 1 receptors and DARPP-32 in Î9-THC-mediated induction of ÎFosB in the mouse forebrain
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Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210
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The basolateral amygdala γ-aminobutyric acidergic system in health and disease
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Endocannabinoid Signaling in Motivation, Reward, and Addiction: Influences on Mesocorticolimbic Dopamine Function
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Acute and Chronic Ethanol Exposure Differentially Regulate CB1 Receptor Function at Glutamatergic Synapses in the Rat Basolateral Amygdala
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Postnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol (MAGL) does not cause neurodegeneration in neonatal mice
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Enhancement of endocannabinoid signalling protects against cocaine-induced neurotoxicity
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Cannabinoid-dopamine interactions in the physiology and physiopathology of the basal ganglia
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Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 (CB1 ) receptors located on glutamatergic neurons and on astrocytes
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Simultaneous inhibition of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) shares discriminative stimulus effects with â9-THC in mice
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Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons
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A highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons
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Anandamide Depresses Glycinergic and GABAergic Inhibitory Transmissions in Adult Rat Substantia Gelatinosa Neurons
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Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells
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Cannabinoid ReceptorâInteracting Protein 1a Modulates CB1 Receptor Signaling and Regulation
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Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications
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Neuronal expression of CB2 cannabinoid receptor mRNAs in the mouse hippocampus
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The role of cannabinoids in adult neurogenesis
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Differential Pharmacological Regulation of Sensorimotor-Gating Deficit in CB1 Knockout Mice and Associated Neurochemical and Histological Alterations
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An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction
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Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons
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Cannabinoid receptor type 1 agonist ACEA improves motor recovery and protects neurons in ischemic stroke in mice
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Habenular CB1 Receptors Control the Expression of Aversive Memories
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β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling
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Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism
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Active endocannabinoids are secreted on extracellular membrane vesicles
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On the Role of Astroglial Syncytia in Self-Repairing Spiking Neural Networks
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Cannabinoid agonists rearrange synaptic vesicles at excitatory synapses and depress motoneuron activity in vivo
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Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders
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N-stearoyltyrosine protects primary cortical neurons against Aβ(1-40)-induced injury through inhibiting endocannabinoid degradation
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Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 (CB1 ) receptors located on glutamatergic neurons and on astrocytes
-
A Synthetic Cannabinoid MAM-2201 Potently Suppresses Synaptic Transmission via Activation of Presynaptic CB1 Receptors and Reduces Synaptically-Evoked Intracellular Ca2+ Transients in Cerebellar Purkinje Cells
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Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene
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Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats
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N-stearoyltyrosine protects primary cortical neurons against Aβ(1-40)-induced injury through inhibiting endocannabinoid degradation
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Further Evidence for the Neuroplastic Role of Cannabinoids: A Study in Organotypic Hippocampal Slice Cultures
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Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 suppress chronic cerebral hypoperfusion-induced neuronal apoptosis by inhibiting c-Jun N-terminal kinase signaling
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Individual differences and vulnerability to drug addiction: a focus on the endocannabinoid system
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Analysis of calretinin early expression in the rat hippocampus after beta amyloid (1-42) peptide injection
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2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons
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Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla
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The interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats
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Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-endoccannabinoid receptor in the ventral mesencephalon
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Emerging concepts of pain therapy based on neuronal mechanisms
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Potential of the cannabinoid CB2 receptor as a pharmacological target against inflammation in Parkinsonâs disease
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Inhibition of FAAH reduces nitroglycerin-induced migraine-like pain and trigeminal neuronal hyperactivity in mice
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Enhanced function of inhibitory presynaptic cannabinoid CB1 receptors on sympathetic nerves of DOCA-salt hypertensive rats
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The effect of endocannabinoid system in ischemia-reperfusion injury: a friend or a foe?
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Chronic ethanol exposure decreases CB1 receptor function at GABAergic synapses in the rat central amygdala
-
Astroglial type-1 cannabinoid receptors (CB1): A new player in the tripartite synapse
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Layer-specific endocannabinoid-mediated LTD of GABAergic neurotransmission onto principal neurons in mouse visual cortex
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Involvement of cannabinoid receptors in infrasonic noise-induced neuronal impairment
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Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release
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Colocalization of cannabinoid receptor 1 with somatostatin and neuronal nitric oxide synthase in rat brain hippocampus
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Endocannabinoid signaling mechanisms in the substantia nigra pars reticulata modulate GABAergic nigrotectal pathways in mice threatened by urutu-cruzeiro venomous pit viper snake
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Effect of Homocysteine on Voltage-Gated Sodium Channel Currents in Primary Cultured Rat Caudate Nucleus Neurons and Its Modulation by 2-Arachidonylglycerol
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Comparative effects of parathion and chlorpyrifos on endocannabinoid and endocannabinoid-like lipid metabolites in rat striatum
-
ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs
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Physiological roles for the subfornical organ â A dynamic transcriptome shaped by autonomic state
-
Neuroprotective mechanisms of cannabinoids in brain ischemia and neurodegenerative disorders
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Pro-inflammatory obesity in aged cannabinoid-2 receptor deficient mice
-
Genetic Manipulation of the Endocannabinoid System
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Neuroprotective Effect Is Driven Through the Upregulation of CB1 Receptor in Experimental Autoimmune Encephalomyelitis
-
Chronic stress and peripheral pain: Evidence for distinct, region-specific changes in visceral and somatosensory pain regulatory pathways
-
Intracellular postsynaptic cannabinoid receptors link thyrotropin-releasing hormone receptors to TRPC-like channels in thalamic paraventricular nucleus neurons
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Excitatory drive from the subthalamic nucleus attenuates GABAergic transmission in the Substantia Nigra pars compacta via endocannabinoids
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Dopamine-dependent CB1 receptor dysfunction at corticostriatal synapses in homozygous PINK1 knockout mice
-
The brain in bone and fuel metabolism
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Maternal separation and early stress cause long-lasting effects on dopaminergic and endocannabinergic systems and alters dendritic morphology in the nucleus accumbens and frontal cortex in rats
-
The neuroprotection of cannabidiol against MPP+-induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinsonâs disease
-
The interactive role of CB1 and GABAB receptors in hippocampal synaptic plasticity in rats
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The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestinal Tract
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Cannabinoid Transmission in the Hippocampus Activates Nucleus Accumbens Neurons and Modulates Reward and Aversion-Related Emotional Salience
-
Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release
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Oxytocin Enhances Pleasure of Social Interactions by Stimulating Production of âBliss Moleculeâ
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Cannabinoid Receptors May Control Aversive Memories
-
Expression and Function of the Endocannabinoid System in the Retina and the Visual Brain
-
Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta
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GABABR-Dependent Long-Term Depression at Hippocampal Synapses between CB1- Positive Interneurons and CA1 Pyramidal Cells
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GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic Inputs
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Endogenous and Synthetic Cannabinoids as Therapeutics in Retinal Disease
-
Systematic Review of Pharmacological Properties of the Oligodendrocyte Lineage
-
Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses
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Estrogen Receptor Beta and 2-arachidonoylglycerol Mediate the Suppressive Effects of Estradiol on Frequency of Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons of Metestrous Mice: An Acute Slice Electrophysiological Study
-
Cannabis for posttraumatic stress disorder: A neurobiological approach to treatment
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Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans
-
Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder
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Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum
-
Cannabinoid receptor type-1: breaking the dogmas
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p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus
-
Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation
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Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimerâs disease
-
Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
-
Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice
-
Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors
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Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
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L-type calcium channels and MAP kinase contribute to thyrotropin-releasing hormone induced depolarization in thalamic paraventricular nucleus neurons
-
Medullary Endocannabinoids Contribute to the Differential Resting Baroreflex Sensitivity in Rats with Altered Brain Renin-Angiotensin System Expression
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Effect of interaction between acute administration of morphine and cannabinoid compounds on spontaneous excitatory and inhibitory postsynaptic currents of magnocellular neurons of supraoptic nucleus
-
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid mediated disinhibition of dopaminergic neurons
-
Endocannabinoids and Heterogeneity of Glial Cells in Brain Function
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Orchestrated activation of mGluR5 and CB1 promotes neuroprotection
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A role of CB1R in inducing θ-rhythm coordination between the gustatory and gastrointestinal insula
-
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders
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Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex
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fMRI study of neural sensitization to hedonic stimuli in long-term, daily cannabis users
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Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species
-
Cannabinoids reverse the effects of early stress on neurocognitive performance in adulthood
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Ontogeny of sensorimotor gating and short-term memory processing throughout the adolescent period in rats
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Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy.
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Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist
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Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling
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CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinsonâs disease
-
Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids
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Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission
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Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
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Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure.
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Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway
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Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk
-
Coordinated regulation of endocannabinoid-mediated retrograde synaptic suppression in the cerebellum by neuronal and astrocytic monoacylglycerol lipase
-
Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32
-
Alteration of SLP2âlike immunolabeling in mitochondria signifies early cellular damage in developing and adult mouse brain
-
Cannabidiol attenuates OGD/R-induced damage by enhancing mitochondrial bioenergetics and modulating glucose metabolism via pentose-phosphate pathway in hippocampal neurons
-
Benefits from Cannabinoids
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Suppressing Schizophrenia Symptoms Without Side Effects: Mouse Study
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Acute Neurologic Disorder from an Inhibitor of Fatty Acid Amide Hydrolase
-
Physiological impact of CB1 receptor expression by hippocampal GABAergic interneurons
-
Major dorsoventral differences in the modulation of the local CA1 hippocampal network by NMDA, mGlu5, adenosine A2A and cannabinoid CB1 receptors
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The endocannabinoid system and neuropathic pain
-
Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy
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Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy
-
Stimulation of cannabinoid CB1 receptors prevents nerve-mediated airway hyperreactivity in NGF-induced inflammation in mouse airways
-
The Hyperpolarization-Activated Cation Current Ih: The Missing Link Connecting Cannabinoids to Cognition
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Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation
-
Antagonism of dopamine receptor 2 long (D2L) affects cannabinoid receptor 1 (CB1) signaling in a cell culture model of striatal medium spiny projection neurons
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Targeting the cannabinoid CB2 receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice.
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Distinct neuronal activation patterns are associated with PCP-induced social withdrawal and its reversal by the endocannabinoid-enhancing drug URB597.
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Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain.
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WHEREâs MY ENTOURAGE? THE CURIOUS CASE OF 2-oleoylglycerol, 2- linolenoylglycerol, and 2-palmitoylglycerol.
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Endocannabinoid 2-Arachidonoylglycerol Suppresses LPS-Induced Inhibition of A-Type Potassium Channel Currents in Caudate Nucleus Neurons Through CB1 Receptor
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Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus
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Stimulated CB1 Cannabinoid Receptor Inducing Ischemic Tolerance and Protecting Neuron from Cerebral Ischemia.
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Direct presynaptic and indirect astrocyte-mediated mechanisms both contribute to endocannabinoid signaling in the pedunculopontine nucleus of mice.
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Phytocannabinoids and cannabimimetic drugs: recent patents in central nervous system disorders.
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Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic Hyperexcitability.
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Differences in Chloride Gradients Allow for Three Distinct Types of Synaptic Modulation by Endocannabinoids.
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Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons.
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Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays.
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Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.
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Reduced Noradrenergic Signaling in the Spleen Capsule in the Absence of CB1 and CB2 Cannabinoid Receptors.
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Upregulation of the cannabinoid CB2 receptor in environmental and viral inflammation driven rat models of Parkinsonâs disease.
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Ischemic Stroke, Excitatory Amino Acids Toxicity and the Adjustment of Acupuncture Intervention
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FABP1 in wonderland.
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Cannabinoids and Neuro-Inflammation: Regulation of Brain Immune Response.
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Microglia activation states and cannabinoid system: Therapeutic implications.
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Inhibitors of diacylglycerol lipases in neurodegenerative and metabolic disorders.
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Expression of the Endocannabinoid Receptor 1 in Human Stroke: An Autoptic Study.
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Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 may protect against cognitive impairment in rats of chronic cerebral hypoperfusion via PI3K/AKT signaling.
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Projection-Specific Dynamic Regulation of Inhibition in Amygdala Micro-Circuits
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Acute Stress Suppresses Synaptic Inhibition and Increases Anxiety via Endocannabinoid Release in the Basolateral Amygdala.
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Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation.
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Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools, implications for endocannabinoid signaling.
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PAK1 regulates inhibitory synaptic function via a novel mechanism mediated by endocannabinoids.
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Cannabinoids: Glutamatergic Transmission and Kynurenines.
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Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids.
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Functions of synapse adhesion molecules neurexin/neurexins and neurodevelopmental disorders.
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Interaction between hippocampal serotonin and cannabinoid systems in reactivity to spatial and object novelty detection.
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Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal.
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Chronic stress leads to epigenetic dysregulation of neuropeptide-Y and cannabinoid CB1 receptor in the mouse cingulate cortex.
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Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism.
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Descending serotonergic and noradrenergic systems do not regulate the antipruritic effects of cannabinoids.
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The central cannabinoid receptor type-2 (CB2) and chronic pain.
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Regulation of fear extinction by long-term depression: the roles of endocannabinoids and brain derived neurotrophic factor.
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The cannabinoid beta-caryophyllene (BCP) induces neuritogenesis in PC12 cells by a cannabinoid-receptor-independent mechanism.
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Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia.
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Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke.
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Cannabidiol Activates Neuronal Precursor Genes in Human Gingival Mesenchymal Stromal Cells.
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Role of Cannabinoid Receptor Type 1 in Tibial and Pudendal Neuromodulation of Bladder Overactivity in Cats.
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Inflammation of peripheral tissues and injury to peripheral nerves induce diferring effects in the expression of the calcium-sensitive anandamide-synthesising enzyme and related molecules in rat primary sensory neurons.
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Inhibitors of oxidative and hydrolytic endocannabinoid degradation do not enhance depolarization-induced suppression of excitation on dorsal cochlear nucleus glycinergic neurons.
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Muscarinic acetylcholine receptors control baseline activity and Hebbian stimulus-timing dependent plasticity in fusiform cells of the dorsal cochlear nucleus.
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Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients
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Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum. (link to download â
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Brain cannabinoid receptor 2: expression, function and modulation.
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(S)Pot on Mitochondria: Cannabinoids Disrupt Cellular Respiration to Limit Neuronal Activity
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N-Oleoylglycine-induced hyperphagia was associated with the activation of AgRP neuron by CB1R.
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Effect of inhibition of fatty acid amide hydrolase on MPTP-induced dopaminergic neuronal damage.
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Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain
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Antihyperalgesic effect of CB1 receptor activation involves the modulation of P2X3 receptor in the primary afferent neuron
NEUROPATHIC PAIN (151)
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Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
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R-Flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids
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Pharmacological Treatment of Painful HIV-Associated Sensory Neuropathy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
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Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
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Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain
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Combination Of Cannabinoids For The Treatment Of Peripheral Neuropathic Pain US 2010/ 0035978 A1 Feb. 11, 2010
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Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide
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AMELIORATIVE POTENTIAL OF CANNABIS SATIVA EXTRACT ON DIABETES INDUCED NEUROPATHIC PAIN IN RATS
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An Open-Label Comparison of Nabilone and Gabapentin as Adjuvant Therapy or Monotherapy in the Management of Neuropathic Pain in Patients with Peripheral Neuropathy
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Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study
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Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain
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Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice
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Cannabinoid Agonists Inhibit Neuropathic Pain Induced by Brachial Plexus Avulsion in Mice by Affecting Glial Cells and MAP Kinases
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Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain
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Cannabinoids for Treatment of Chronic Non-Cancer Pain, a Systematic Review of Randomized Trials
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Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism
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Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
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Activation of spinal and supraspinal cannabinoid-1 receptors leads to anti-nociception in a rat model of neuropathic spinal cord injury pain
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Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury
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Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy induced painful neuropathy
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Prescribing Cannabis for Harm Reduction
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The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy
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Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series
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Endocannabinoids in nervous system health and disease: the big picture in a nutshell
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The Therapeutic Potential of Cannabis and Cannabinoids
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The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica
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Dynamic changes to the endocannabinoid system in models of chronic pain
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Low-Dose Vaporized Cannabis Significantly Improves Neuropathic Pain
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Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid / endovanilloid system
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Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System
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The Novel Reversible Fatty Acid Amide Hydrolase Inhibitor ST4070 Increases Endo-cannabinoid Brain Levels and Counteracts Neuropathic Pain in Different Animal Models
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Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
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Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment
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Local Peripheral Effects of β-Caryophyllene through CB2 Receptors in Neuropathic Pain in Mice
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Multimodal stepped care approach with acupuncture and PPAR-α agonist palmitoylethanolamide in the treatment of a patient with multiple sclerosis and central neuropathic pain.
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The atypical cannabinoid O-1602 increases hind paw sensitisation in the chronic constriction injury model of neuropathic pain
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Cannabinoid agonist WIN 55,212-2 prevents the development of paclitaxel-induced peripheral neuropathy in rats. Possible involvement of spinal glial cells
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Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain
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Characterization of cannabinoid-induced relief of neuropathic pain in rat models of type 1 and type 2 diabetes
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A Randomized, Double-Blind, Placebo Controlled, Parallel Assignment, Flexible Dose, Efficacy Study of Nabilone as Adjuvant in the Treatment of Diabetic Peripheral Neuropathic Pain Using an Enriched Enrollment Randomized Withdrawal Design (S38.003)
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An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain
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Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats
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A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
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The Major Brain Endocannabinoid 2-AG Controls Neuropathic Pain and Mechanical Hyperalgesia in Patients with Neuromyelitis Optica
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Drug Design for Neuropathic Pain Regulation from Traditional Chinese Medicine
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Full Inhibition of Spinal FAAH Leads to TRPV1-Mediated Analgesic Effects in Neuropathic Rats and Possible Lipoxygenase-Mediated Remodeling of Anandamide Metabolism
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The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain
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The endocannabinoid system, cannabinoids, and pain
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Bilateral changes of cannabinoid receptor type 2 protein and mRNA in the dorsal root ganglia of a rat neuropathic pain model
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A Double-Blind, Placebo-Controlled, Crossover Pilot Trial With Extension Using an Oral Mucosal Cannabinoid Extract for Treatment of Chemotherapy-Induced Neuropathic Pain
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A Double-Blind, Placebo-Controlled, Crossover Pilot Trial With Extension Using an Oral Mucosal Cannabinoid Extract for Treatment of Chemotherapy-Induced Neuropathic Pain
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Anandamide deficiency and heightened neuropathic pain in aged mice
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Non-Neuronal Cell Modulation Relieves Neuropathic Pain: Efficacy of the Endogenous Lipid Palmitoylethanolamide
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Palmitoylethanolamide Reduces Formalin-Induced Neuropathic-Like Behaviour Through Spinal Glial/Microglial Phenotypical Changes in Mice
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Different Classes of CB2 Ligands Potentially Useful in the Treatment of Pain
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Medicinal Cannabis and Painful Sensory Neuropathy
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Therapeutic potential of cannabinoid medicines
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Characterisation of cannabinoid-induced relief of neuropathic pain in a rat model of cisplatin-induced neuropathy
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Palmitoylethanolamide is a New Possible Pharmacological Treatment for the Inflammation Associated with Trauma
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Activation of spinal cannabinoid cb2 receptors inhibits neuropathic pain in streptozotocin-induced diabetic mice
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Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CB1 and CB2 receptors
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Non-neuronal cell modulation relieves neuropathic pain: efficacy of the endogenous lipid palmitoylethanolamide
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Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy
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Prescribing smoked cannabis for chronic noncancer pain: Preliminary recommendations
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Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy
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Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery
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Therapeutic benefits of cannabis: a patient survey
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CB2 cannabinoid receptors as a therapeutic target â What does the future hold?
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Alterations in the anandamide metabolism in the development of neuropathic pain
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NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors
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Celastrol Attenuates Inflammatory and Neuropathic Pain Mediated by Cannabinoid Receptor Type 2
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Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells
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Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats
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Effects of repeated dosing with mechanistically distinct antinociceptive ligands in a rat model of neuropathic spinal cord injury pain
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Effects of repeated dosing with mechanistically distinct antinociceptive ligands in a rat model of neuropathic spinal cord injury pain
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The cannabinoid CBâ receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain
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JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy
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JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy
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Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models
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Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy
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Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy
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Dual inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice
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Dual inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice
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Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury
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The Pharmacokinetics, Efficacy, Safety, and Ease of Use of a Novel Portable Metered Dose Cannabis Inhaler in Patients With Chronic Neuropathic Pain: A Phase 1a Study
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The Pharmacokinetics, Efficacy, Safety, and Ease of Use of a Novel Portable MeteredDose Cannabis Inhaler in Patients With Chronic Neuropathic Pain: A Phase 1a Study
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Pharmacological management of chronic neuropathic pain: Revised consensus statement from the Canadian Pain Society. (link to PDF â
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A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment
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Endocannabinoids and neuropathic pain: focus on neuron-glia and endocannabinoid neurotrophin interactions
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Involvement of the endocannabinoid system in osteoarthritis pain
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Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands
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Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol
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Cannabinoids for Neuropathic Pain
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Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue
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There is evidence for the use of cannabinoids for symptomatic treatment of multiple sclerosis
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Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy
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Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users
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Palmitoylethanolamide, a naturally occurring disease-modifying agent in neuropathic pain
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The spinal anti-inflammatory mechanism of motor cortex stimulation: cause of success and refractoriness in neuropathic pain?
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Nabilone as an Adjunctive to Gabapentin for Multiple Sclerosis-Induced Neuropathic Pain: A Randomized Controlled Trial
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Cannabis in cancer care
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Coadministration of indomethacin and minocycline attenuates established paclitaxel induced neuropathic thermal hyperalgesia: Involvement of cannabinoid CB1 receptors
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Efficacy and adverse effects of medical marijuana for chronic noncancer pain: Systematic review of randomized controlled trials
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TRPV1 channel inhibition contributes to the antinociceptive effects of Croton macrostachyus extract in mice
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CB1 Knockout Mice Unveil Sustained CB2-Mediated Anti-Allodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain
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Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
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Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review
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Combined inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice
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Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy
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A Cannabinoid CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects
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Spinal RGS4 inhibition effectively attenuates neuropathic hyperalgesia and restores cannabinoid receptor type 1 signaling
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Inhaled Cannabis for Chronic Neuropathic Pain: A Meta-analysis of Individual Patient Data
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Tonic Modulation of Nociceptive Behavior and Allodynia by Cannabinoid Receptors in Formalin Test in Rats
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Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2)
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The entourage effect: Synergistic actions of plant cannabinoids
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The Effectiveness of Cannabinoids in the Management of Chronic Nonmalignant Neuropathic Pain: A Systematic Review
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Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy
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CB1 receptors modulate affective behaviour induced by neuropathic pain
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N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution
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Minimizing chemotherapy-induced peripheral neuropathy: preclinical and clinical development of new perspectives
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Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence
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The Efficacy of Eslicarbazepine Acetate in Models of Trigeminal, Neuropathic, and Visceral Pain: The Involvement of 5-HT1B/1D Serotonergic and CB1/CB2 Cannabinoid Receptors
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Analysis of the anti-allodynic effects of combination of a synthetic cannabinoid and a selective noradrenaline re-uptake inhibitor in nerve injury-induced neuropathic mice
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Prescribing medical cannabis in Canada: Are we being too cautious?
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Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine neuropathic pain model
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Integrating cannabis into clinical cancer care
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The effect of spinally administered WIN 55,212-2, a cannabinoid agonist, on thermal pain sensitivity in diabetic rats
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Neuropathic Pain Treatment: Still a Challenge
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Cannabinoid Buccal Spray for Chronic Non-Cancer or Neuropathic Pain: A Review of Clinical Effectiveness, Safety, and Guidelines
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A preliminary evaluation of the relationship of cannabinoid blood concentrations with the analgesic response to vaporized cannabis
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The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model
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Using Medical Cannabis in an Oncology Practice
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Evaluating Sativex® in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis
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Medical use of cannabis products : Lessons to be learned from Israel and Canada
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The endocannabinoid system and neuropathic pain
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Efficacy, tolerability and safety of cannabinoids for chronic neuropathic pain : A systematic review of randomized controlled studies (scroll down for English version)
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Nabilone for the Management of Pain
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Polypharmacological Properties and Therapeutic Potential of β-Caryophyllene: a Dietary Phytocannabinoid of Pharmaceutical Promise
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Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy
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The role of carbon monoxide on the anti-nociceptive effects and expression of cannabinoid 2 receptors during painful diabetic neuropathy in mice
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Mesoporous Silica Particles as a Multifunctional Delivery System for Pain Relief in Experimental Neuropathy
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Opioid and cannabinoid synergy in a mouse neuropathic pain model
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The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain.
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An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain from Spinal Cord Injury and Disease
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Peripherally selective cannabinoid 1 receptor (CB1R) agonists for the treatment of neuropathic pain
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Progress in study on endocannabinoids and cannabinoid receptors in the treatment for neuropathic pain
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Activation of Cannabinoid Receptor 2 Attenuates Mechanical Allodynia and Neuroinflammatory Responses in a Chronic Post-Ischemic Pain Model of Complex Regional Pain Syndrome Type I in Rats
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The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice
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Inflammation of peripheral tissues and injury to peripheral nerves induce diferring effects in the expression of the calcium-sensitive anandamide-synthesising enzyme and related molecules in rat primary sensory neurons
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Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation