Medisinsk forskning på cannabis
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OBESITY/ADIPOSE TISSUE (313)
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Alterations in the hippocampal endocannabinoid system in diet-induced obese mice
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Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients
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Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype
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Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution
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The endocannabinoid system links gut microbiota to adipogenesis
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CD36 gene deletion decreases oleoylethanolamide levels in small intestine of freefeeding mice
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A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain
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The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure
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Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients
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The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food reinforced behavior
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Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity
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A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia
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Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes?
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Modulation of Adipocyte Biology by Î9-Tetrahydrocannabinol
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Cannabidiol Attenuates the Appetitive Effects of Î9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis
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Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia
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A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents
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A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes
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A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study
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The endocannabinoid system modulates the valence of the emotion associated to food ingestion
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A randomised, double blind, placebo controlled, parallel group, pilot study of 1:1 and 20:1 ratio of formulated GW42003 : GW42004 plus GW42003 and GW42004 alone in the treatment of dyslipidaemia in subjects with Type 2 diabetes
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Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age
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Analysis of gene expression pattern reveals potential targets of dietary oleoyl-ethanolamide in reducing body fat gain in C3H mice
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G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population
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Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood
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Cannabis Use and Obesity and Young Adults
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Fructose affects enzymes involved in the synthesis and degradation of hypothalamic endocannabinoids
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Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function
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Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects
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Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice
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Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice
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The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans
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Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study
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Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine
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The association of the rs1049353 polymorphism of the CNR1 gene with hypo-adiponectinemia
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The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabantâs antiobesity effects in mice
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Gadolinium-HU-308-incorporated micelles
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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise
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385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population
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Greasing the wheels of managing overweight and obesity with omega-3 fatty acids
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Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes
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Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity
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Obesity and Cannabis Use: Results From 2 Representative National Surveys
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Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome
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The neutral cannabinoid CBâ receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat
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Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice
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Expression of the cannabinoid system in muscle: effects of a high fat diet and CB1 receptor blockade
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Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss
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Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss
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Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?
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Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?
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Roles of G1359A polymorphism of the cannabinoid receptor gene (CNR1) on weight loss and adipocytokines after a hypocaloric diet
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Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females
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The role of central CB2 cannabinoid receptors on food intake in neonatal chicks
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Endocannabinoid signaling and energy metabolism: a target for dietary intervention
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Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors
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Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle
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Screening of selected Asian spices for anti obesity-related bioactivities
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To Be or Not To Be-Obese
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The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity
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Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function
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Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism
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Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity
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Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men
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Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant
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Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice
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Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences
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Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity
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Over-Expression of Monoacylglycerol Lipase (MGL) in Small Intestine Alters Endocannabinoid Levels and Whole Body Energy Balance, Resulting in Obesity
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Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxy-lipins and Endocannabinoids
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Endocannabinoids measurement in human saliva as potential biomarker of obesity
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Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids
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The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription
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2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism
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2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism
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CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake
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Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice
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Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice
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Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study
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Rimonabant improves obesity but not the overall cardiovascular risk and quality of life, results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE)
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Does rimonabant independently affect free fatty acid and glucose metabolism?
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Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake
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The thrifty lipids: endocannabinoids and the neural control of energy conservation
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Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density
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GPR119 as a fat sensor
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Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters
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Neural Substrates Underlying Interactions between Appetite Stress and Reward
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Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity
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The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats
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Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis
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Diet-dependent modulation of hippocampal expression of endocannabinoid signalingrelated proteins in cannabinoid antagonist-treated obese rats
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Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model
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Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice
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Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice
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Cannabinol and cannabidiol exert opposing effects on rat feeding patterns
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Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats
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Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women
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The role of the endocannabinoid system in eating disorders: pharmacological implications
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The potential use of cannabidiol in the therapy of metabolic syndrome
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Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets
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The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity
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Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms
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New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance
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Fatty acid flux and oxidation are increased by rimonabant in obese women
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Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet
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The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
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The cannabinoid Î(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity
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Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats
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Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men
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Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain
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Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons
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Food for thought: hormonal, experiential, and neural influences on feeding and obesity
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Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies
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Orexin neurons use endocannabinoids to break obesity-induced inhibition
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Effect of high fat-diet and obesity on gastrointestinal motility
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Insulin induces long-term depression of VTA dopamine neurons via endocannabinoids
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Cannabinoids, eating behaviour, and energy homeostasis
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Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes
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Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth
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Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase
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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
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Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines
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Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism
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Effect of Nelumbo nucifera Petal Extracts on Lipase, Adipogenesis, Adipolysis, and Central Receptors of Obesity
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The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome
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A potential role for GPR55 in gastrointestinal functions
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Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action
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Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity
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High fat diet and body weight have different effects on cannabinoid CB1 receptor expression in rat nodose ganglia
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Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity
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Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
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A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2- arachidonoylglycerol with potential anti-obesity effects
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Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets
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Cannabis and Î(9)-tetrahydrocannabinol (THC) for weight loss?
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Endocannabinoids and obesity
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Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21
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Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity
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The endocannabinoid system in obesity
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Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats
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Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway
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Analysis of the âendocannabinoidomeâ in peripheral tissues of obese Zucker rats
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The Role of the Endocannabinoid System in Eating Disorders: Neurochemical and Behavioural Preclinical Evidence
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Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats
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Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice
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Role of Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Poly-morphism) on Weight Loss and Cardiovascular Risk Factors After Liraglutide Treatment in Obese Patients With Diabetes Mellitus Type 2
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Regulation of GPR55 in rat white adipose tissue and serum LPI by nutritional status, gestation, gender and pituitary factors
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The regulation of food intake by the gut-brain axis: implications for obesity
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Concurrent pharmacological modification of cannabinoid-1 and glucagon-like peptide-1 receptor activity affects feeding behavior and body weight in rats fed a free-choice, highcarbohydrate diet
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Effects of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) on weight loss, adipocytokines levels, and insulin resistance after a high polyunsaturated fat diet in obese patients
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Marijuana and Body Weight
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Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat
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Oleoylethanolamide: a novel potential pharmacological alternative to cannabinoid antagonists for the control of appetite
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Vascular targets for cannabinoids: animal and human studies
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Long-term changes in the ghrelin-CB1R axis associated with the maintenance of lower body weight after sleeve gastrectomy
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A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice
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Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice
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The Endocannabinoid System â Back to the Scene of Cardiometabolic Risk Factors Control?
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The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes
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Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects
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Endocannabinoid Receptors Gene Expression in Morbidly Obese Women with Non-alcoholic Fatty Liver Disease
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Dietary Non-Esterified Oleic Acid Decreases the Jejunal Levels of Anorectic NAcylethanolamines
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Effects of chaiyuwendan decoction on endocannabinoids levels in adipose tissue of rats with chronic stress-induced depression
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Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament
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The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet
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Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder
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Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing denovo synthesis of long-chain ceramides
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Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats
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CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin
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Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin (THCv) on Food Reward and Aversion in Healthy Volunteers
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Genetic Sensitivity to the Bitter Taste of 6-n-Propylthiouracil (PROP) and Its Association with Physiological Mechanisms Controlling Body Mass Index (BMI)
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Mitochondria: A Possible Nexus for the Regulation of Energy Homeostasis by the Endocannabinoid System?
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Modulation of plasma N-acylethanolamine levels and physiological parameters by dietary fatty acid composition in humans
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Oleoylethanolamide and Human Neural Responses to Food Stimuli in Obesity
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Baseline Anandamide Levels and Body Weight Impact the Weight Loss Effect of CB1 Receptor Antagonism in Male Rats
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Cannabis use in relation to obesity and insulin resistance in the inuit population
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Endocannabinoid signaling and food addiction
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Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standard chow diets
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Cannabinoid Type 1 (CB1) Receptors on Sim1-Expressing Neurons Regulate Energy Expenditure in Male Mice
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Cannabinoids, eating behaviour, and energy homeostasis
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CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans
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Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond
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Endocannabinoids and energy homeostasis: An update
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The endocannabinoid system and appetite: relevance for food reward
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GPR55: From orphan to metabolic regulator?
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Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed
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Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome
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Gut microbiota and obesity: Role in aetiology and potential therapeutic target
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Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways
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The role of gut hormones in appetite regulation (review)
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The endocannabinoid system: directing eating behavior and macronutrient metabolism
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Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion
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Global deletion of monoacylglycerol lipase in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity
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Leptin Levels Are Negatively Correlated with 2-Arachidonoylglycerol in the Cerebrospinal Fluid of Patients with Osteoarthritis
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Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets
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Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons
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Dietary Triacylglycerols with Palmitic Acid in the sn-2 Position Modulate Levels of NAcylethanolamides in Rat Tissues
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A cannabinoid receptor agonist N-arachidonoyl dopamine inhibits adipocyte differentiation in human mesenchymal stem cells
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The endocannabinoid anandamide during lactation increases body fat content and CB1 receptor levels in mice adipose tissue
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Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
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Tetrahydrocannabivarin (THCv) reduces Default Mode Network and increases Executive Control Network Resting State Functional Connectivity in Healthy Volunteers
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N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte
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The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Child-hood Obesity and Age at Menarche
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Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults
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Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture
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Hypothalamic control of brown adipose tissue thermogenesis
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Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Î9-Tetrahydrocannabinol
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Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle
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METABOLIC EFFECTS OF MARIJUANA USE AMONG BLACKS
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Anti-Obesity Effect of the CB2 Receptor Agonist JWH-015 in Diet-Induced Obese Mice
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Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice
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Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice
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α/β Hydrolase Domain-Containing 6 (ABHD6) Degrades the Late Endosomal / Lysosomal Lipid Bis(monoacylglycero)phosphate
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Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency
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Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency
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Role of the Endocannabinoid System in Diabetes and Diabetic Complications
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Cigarette smoking may modify the association between cannabis use and adiposity in males
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Association of G1359A polymorphism of the cannabinoid receptor gene (CNR1) with macronutrient intakes in obese females
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Polymorphism G1359A of the cannabinoid receptor gene (CNR1): allelic frequencies and influence on cardiovascular risk factors in a multicentre study of Castilla-Leon
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Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoylglycerol and arachidonoyl-ethanolamide, and their metabolites
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Association between paracetamol use in infancy or childhood with body mass index
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Chronic administration with AM251 improves albuminuria and renal tubular structure in obese rats
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Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion
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Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-like Behavior
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Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-arachidonoylglycerol
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Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome
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The emerging role of the endocannabinoid system in the pathogenesis and treatment of kidney diseases
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Participation of the endocannabinoid system (ECS) in the weight-gain and sensitization to LPS exposure in a maternal obesity model
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Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis
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Effects of a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors during 9 Months: Role of a Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism)
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Analysis of FABP4 expression pattern in rump fat deposition and metabolism of Altay sheep
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A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents
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Strain and sex differences in puberty onset and the effects of THC administration on weight gain and brain volumes
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The endocannabinoid system role in the pathogenesis of obesity and depression
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Pro-inflammatory obesity in aged cannabinoid-2 receptor deficient mice
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New insights on the role of the endocannabinoid system in the regulation of energy balance
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Endocannabinoids and Metabolic Disorders
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The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease
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The brain in bone and fuel metabolism
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Deletion of G-protein coupled receptor 55 promotes obesity by reducing physical activity
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Development and validation of an HPLC-MS method for the simultaneous quantification of key oxysterols, endocannabinoids, and ceramides: variations in metabolic syndrome
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Approaches for the development of drugs for treatment of obesity and metabolic syndrome
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Endocannabinoids â at the crossroads between the gut microbiota and host metabolism
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Cell type-specific modulation of lipid mediatorâs formation in murine adipose tissue by omega-3 fatty acids
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Cannabis: a self-medication drug for weight management? The never ending story
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Lipid signaling in adipose tissue: Connecting inflammation & metabolism
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Effects of dietary CLA on n-3 HUFA score and N-acylethanolamides biosynthesis in the liver of obese Zucker rats
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Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation
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Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine neuropathic pain model
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CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunction
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Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring
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Vaccenic acid suppresses intestinal inflammation by increasing the endocannabinoid anandamide and non-cannabinoid signaling molecules in a rat model of the metabolic syndrome
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An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
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New insights into the yin and yang of the endocannabinoid system in health and disease
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A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women
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Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors.
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The potential relevance of the endocannabinoid, 2-arachidonoylglycerol, in diffuse large B-cell lymphoma
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Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes
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Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction
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Endocannabinoids in Feeding Behavior and Energy Homeostasis
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Association between cerebral cannabinoid 1 receptor availability and body mass index in patients with food intake disorders and healthy subjects: a [(18)F]MK-9470 PET study
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Mice Expressing a âHyper-Sensitiveâ Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic
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Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism
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Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature
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Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring
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Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring
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Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance
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Cannabinoid 2 Receptor Agonist Improves Systemic Sensitivity to Insulin in High-Fat Diet/Streptozotocin-Induced Diabetic Mice
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An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
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Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling
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Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome
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α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility
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Endocannabinoid regulation of β-cell functions: Implications for glycemic control and diabetes
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Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice
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Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice
-
Long-Term Effects of Prenatal Exposure to Undernutrition on Cannabinoid Receptor Related Behaviors: Sex and Tissue-Specific Alterations in the mRNA Expression of Cannabinoid Receptors and Lipid Metabolic Regulators
-
Cannabinoid receptor 2 as anti-obesity target: inflammation, fat storage and browning modulation
-
The CB1 neutral antagonist AM4113 retains the therapeutic efficacy of the inverse agonist rimonabant for nicotine dependence and weight loss, with better psychiatric tolerability
-
The inhibitory effect of combination treatment with leptin and cannabinoid CB1 receptor agonist on food intake and body weight gain is mediated by serotonin 1B and 2C receptors (click Full Text Links for
-
Effects of activation of endocannabinoid system on myocardial metabolism (click âICIâ for
-
Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity
-
Sex Differences in Cannabinoid-Regulated Biology: A Focus on Energy Homeostasis
-
G protein-coupled receptor 18: A potential role for endocannabinoid signalling in metabolic dysfunction
-
G protein-coupled receptor 18: A potential role for endocannabinoid signalling in metabolic dysfunction
-
Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition
-
Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity
-
Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity
-
Regulation of Growth Hormone by the Splanchnic Area
-
Role of cannabinoid receptors in renal diseases
-
SGIP1 Alters Internalization and Modulates Signaling of Activated Cannabinoid Receptor 1 in Biased Manner
-
Cannabidiol promotes browning in 3T3-L1 adipocytes
-
Fatty Acid Binding Protein-1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias
-
Driving the need to feed: Insight into the collaborative interaction between ghrelin and endocannabinoid systems in modulating brain reward systems
-
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice
-
Decision-Making Does not Moderate the Association between Cannabis Use and Body Mass Index among Adolescent Cannabis Users
-
Genetic polymorphisms in genes related to risk-taking behaviours predicting body mass index trajectory among Mexican American adolescents
-
Simultaneous HPLC-APCI-MS/MS quantification of endogenous cannabinoids and glucocorticoids in hair
-
LINOLEIC ACID AND THE PATHOGENESIS OF OBESITY
-
Endocannabionoid System in Neurological Disorders
-
Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation
-
Cannabis and a lower BMI in psychosis: What is the role of AKT1?
-
Disturbances of sleep and circadian rhythms: novel risk factors for obesity
-
Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome
-
Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation
-
Marijuana Use and Type 2 Diabetes Mellitus: a Review
-
The role of perivascular adipose tissue in obesity-induced vascular dysfunction
-
Fabp1 gene ablation inhibits high fat diet-induced increase in brain endocannabinoids
-
Cannabimimetic phytochemicals in the diet â an evolutionary link to food selection and metabolic stress adaptation?
-
Got Munchies? Estimating the Relationship between Marijuana Use and Body Mass Index
-
Using proteomics to discover novel biomarkers for fatty liver development and response to CB1R antagonist treatment in an obese mouse model
-
Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity
-
Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function
-
Association Between Use of Cannabis in Adolescence and Weight Change into Midlife (link to
-
Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity
OBSESSIVE COMPULSIVE DISORDER/OCD (11)
-
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
-
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay
-
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Î(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour
-
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
-
Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
-
Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor
-
Cannabidiol reverses the mCPP-induced increase in marble-burying behavior
-
β-Caryophyllene, a CB2 Receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice
-
Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine
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Cannabidiol as a Potential Treatment for Anxiety Disorders
-
Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation
OLDER ADULTS (33)
-
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention
-
Prevalences of illicit drug use in people aged 50 years and over from two surveys
-
Statistics on cannabis users skew perceptions of cannabis use
-
Still Dazed and Confused: Midlife Marijuana Use by the Baby Boom Generation
-
New insights into the physiology of bone regulation: the role of neuro-hormones
-
Therapeutic benefits of cannabis: a patient survey
-
The endocannabinoid system and appetite: relevance for food reward
-
Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial
-
The successful use of dronabinol for failure to thrive secondary to intestinal dysmotility
-
Use of Prescription Pain Medications Among Medical Cannabis Patients: Comparisons of Pain Levels, Functioning, and Patterns of Alcohol and Other Drug Use
-
PROGRESS REPORT Compassionate Use of Medical Cannabis Pilot Program Act July 1,
-
Responsible and controlled use: Older cannabis users and harm reduction
-
Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9-tetrahydrocannabinol in older persons with dementia
-
The Effect of Medical Marijuana Laws on Body Weight
-
THE EFFECT OF MEDICAL MARIJUANA LAWS ON BODY WEIGHT
-
Cannabinoids in late-onset Alzheimerâs disease
-
A safer alternative: Cannabis substitution as harm reduction
-
Substituting cannabis for prescription drugs, alcohol and other substances among medical cannabis patients: The impact of contextual factors
-
With education, nurses can help to bridge the marijuana gap
-
Patterns of cannabis use in patients with Inflammatory Bowel Disease: A population based analysis
-
National Estimates of Marijuana Use and Related Indicators â National Survey on Drug Use and Health, United States, 2002â
-
Medical Marijuana Laws Reduce Prescription Medication Use In Medicare Part D
-
Older-adult marijuana users and ex-users: Comparisons of sociodemographic characteristics and mental and substance use disorders
-
Agitation in Alzheimer Disease as a Qualifying Condition for Medical Marijuana in the United States
-
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets
-
Bongs and baby boomers: Trends in cannabis use among older Australians
-
Older marijuana users: Life stressors and perceived social support
-
Pros and cons of medical cannabis use by people with chronic brain disorders
-
The Impact of Medical Marijuana Laws on the Labor Supply and Health of Older Adults: Evidence from the Health and Retirement Study
-
Accidental cannabis poisoning in the elderly
-
Demographic trends among older cannabis users in the United States, 2006â13
-
From adolescent to elder rats: Motivation for palatable food and cannabinoids receptors
-
Protective effects of trans-caryophyllene on maintaining osteoblast function
OMEGA-3/CB1 CONNECTION (100)
-
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines
-
Maternal Dietary Fat Determines Metabolic Profile and the Magnitude of Endo-cannabinoid Inhibition of the Stress Response in Neonatal Rat Offspring
-
Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma
-
Pitfalls in the sample preparation and analysis of N-acylethanolamines
-
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood
-
Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice
-
Fish oil promotes survival and protects against cognitive decline in severely under-nourished mice by normalizing satiety signals
-
A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development
-
Greasing the wheels of managing overweight and obesity with omega-3 fatty acids
-
Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets
-
N-Docosahhexanoyllethanolamide promotes development of hippocampal neurons
-
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions
-
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions Figure 1: n-3/n-6 PUFA dietary imbalance alters PUFAs level in mouse brain
-
Endocannabinoid signaling and energy metabolism: a target for dietary intervention
-
Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines
-
Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome
-
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids
-
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity
-
Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids
-
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues
-
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids â From fishy endocannabinoids to potential leads
-
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids
-
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds
-
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice
-
The biochemical complexity of the endocannabinoid system with some remarks on stress and related disorders: a minireview
-
Nutritional n-3 polyunsaturated fatty acids deficiency alters cannabinoid receptor signaling pathway in the brain and associated anxiety-like behavior in mice
-
Essential fatty acids and lipid mediators. Endocannabinoids
-
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators
-
Effect of omega-3 polyunsaturated fatty acids on the endocannabinoid system in osteoblast-like cells and muscle
-
Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure
-
Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle
-
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective
-
Effect of dietary fat type on anxiety-like and depression-like behavior in mice
-
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men
-
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex
-
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective
-
Effect of dietary fat type on anxiety-like and depression-like behavior in mice
-
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men
-
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex
-
Nutritional properties of dietary omega-3-enriched phospholipids
-
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients
-
Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function
-
Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
-
Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection
-
PUFA-derived endocannabinoids: an overview
-
Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury
-
Chemical Composition and Characterization of Hemp (Cannabis sativa) Seed oil and essential fatty acids by HPLC Method
-
Acyl migration evaluation in monoacylglycerols from Echium plantagineum seed oil and Marinol
-
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
-
DHA prevents altered 5-HT1(A), 5-HT2(A), CB1 and GABA(A) receptor binding densities in the brain of male rats fed a high-saturated-fat diet
-
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids and obesity
-
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function
-
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts
-
Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived MediatorsSustains Homeostatic Synaptic and Circuitry Integrity
-
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target?
-
Modulation of plasma N-acylethanolamine levels and physiological parameters by dietary fatty acid composition in humans
-
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
-
Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion
-
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars
-
Endocannabinoid signaling and its regulation by nutrients
-
Hempseed oil induces reactive oxygen species- and C/EBP homologous protein-mediated apoptosis in MH7A human rheumatoid arthritis fibroblast-like synovial cells
-
Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity
-
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content
-
Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity
-
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content
-
Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC (bone mineral content)
-
Relationship between cannabinoids content and composition of fatty acids in hempseed oils
-
Omega-3 fatty acid production from enzyme saccharified hemp hydrolysate using a novel marine thraustochytrid strain
-
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages
-
The endocannabinoid system: directing eating behavior and macronutrient metabolism
-
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice
-
Nitric oxide secretion in human conjunctival fibroblasts is inhibited by alpha linolenic acid
-
Fetal endocannabinoids orchestrate the organization of pancreatic islet micro-architecture
-
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture
-
Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice
-
Polyunsaturated fatty acids and inflammation
-
Polyunsaturated fatty acids and inflammation
-
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress
-
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress
-
Distribution of Bioactive Lipid Mediators in Human Skin
-
Fatty acids, endocannabinoids and inflammation
-
Biosynthesis and Fate of Endocannabinoids
-
Cell type-specific modulation of lipid mediatorâs formation in murine adipose tissue by omega-3 fatty acids
-
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
-
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
-
Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid
-
Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice
-
Effects of Different Levels of Hemp Seed (Cannabis Sativa L.) and Dextran Oligosaccharide on Growth Performance and Antibody Titer Response of Broiler Chickens
-
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice
-
Lifelong imbalanced linoleic/alpha-linolenic acid intake impairs emotional and cognitive behavior in adult rats via changes in brain endocannabinoid system. (click âFull Text Linksâ to
-
Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition
-
Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation
-
Distinctive effects of eicosapentaenoic and docosahexaenoic acids in regulating neural stem cell fate are mediated via endocannabinoid signalling pathways
-
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice
-
Analysis of Omega-3 Fatty Acid Derived N-Acylethanolamines in Biological Matrices
-
Docosahexaenoic acid attenuates in endocannabinoid synthesis in RAW 264.7 macrophages activated with benzo(a)pyrene and lipopolysaccharide
-
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study
-
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets
-
Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23âIL-17 signalling in macrophages
-
Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohnâs Disease and Ulcerative Colitis
OMEGA-6/ENDOCANNABINOID CONNECTION (46)
-
Exposure to a high-fat diet decreases sensitivity to Î9-tetrahydrocannabinol-induced motor effects in female rats
-
Pitfalls in the sample preparation and analysis of N-acylethanolamines
-
Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets
-
Endocannabinoid signaling and energy metabolism: a target for dietary intervention
-
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice
-
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids â From fishy endocannabinoids to potential leads
-
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity
-
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues
-
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds
-
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators
-
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective
-
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex
-
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients
-
PUFA-derived endocannabinoids: an overview
-
Chemical Composition and Characterization of Hemp (Cannabis sativa) Seed oil and essential fatty acids by HPLC Method
-
Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system
-
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function
-
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts
-
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target?
-
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
-
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars
-
Endocannabinoid signaling and its regulation by nutrients
-
Gamma-linolenic acid egg production enriched with hemp seed oil and evening primrose oil in diet of laying hens
-
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content
-
Relationship between cannabinoids content and composition of fatty acids in hemp seed oils
-
The endocannabinoid system: directing eating behavior and macronutrient metabolism
-
Lipid mediator profile in vernix caseosa reflects skin barrier development
-
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice
-
Polyunsaturated fatty acids and inflammation
-
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress
-
Fatty acids, endocannabinoids and inflammation
-
Biosynthesis and Fate of Endocannabinoids
-
Lipid signaling in adipose tissue: Connecting inflammation & metabolism
-
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
-
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
-
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
-
Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid
-
Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice
-
Effects of Different Levels of Hemp Seed (Cannabis Sativa L.) and Dextran Oligosaccharide on Growth Performance and Antibody Titer Response of Broiler Chickens
-
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin /+ transgenic mice
-
Lifelong imbalanced linoleic/alpha-linolenic acid intake impairs emotional and cognitive behavior in adult rats via changes in brain endocannabinoid system. (click âFull Text Linksâ to
-
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice
-
Dietary conjugated linoleic acid supplementation alters the expression of genes involved in the endocannabinoid system in the bovine endometrium and increases plasma progesterone concentrations
-
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study
-
LINOLEIC ACID AND THE PATHOGENESIS OF OBESITY
-
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets
OMEGA-9 (5)
-
Pitfalls in the sample preparation and analysis of N-acylethanolamines
-
Multiple Changes in Peptide and Lipid Expression Associated with Regeneration in the Nervous System of the Medicinal Leech
-
Targeted mutation of Î12 and Î15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil
-
Your Next Cooking Oil Could Come From Hemp
-
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice
ORGAN TRANSPLANTS (22)
-
Do cannabinoids have a therapeutic role in transplantation?
-
Denial of hepatic transplantation on the basis of smoking: is it ethical?
-
Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model
-
Prolonged excretion half-life of 11-nor-9-carboxy-Îâ¹-THC following cessation in a chronic, heavy marijuana user: implications for liver transplant assessment
-
Cannabinoids Inhibit T-cells via Cannabinoid Receptor 2 in an In Vitro Assay for Graft Rejection, the Mixed Lymphocyte Reaction
-
Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury
-
Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study
-
Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study
-
Effects of Cannabinoids on T-cell Function and Resistance to Infection
-
A CB2-Selective Cannabinoid Suppresses T-Cell Activities and Increases Tregs and IL-10
-
Î9-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells
-
Cannabidiol for the Prevention of Graft-Versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study
-
The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report
-
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine
-
Effects of Cannabinoids on T-cell Function and Resistance to Infection
-
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine
-
The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts
-
The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts
-
High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana
-
Cannabidiol limits Tcell-mediated chronic autoimmune myocarditis: implications to autoimmune disorders and organ transplantation
-
Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type-2 Diabetes
-
Influence of history of cannabis smoking in selected donors on the outcomes of lung transplantation
ORGANIC ACIDEMIAS (2)
-
The effect of WIN 55,212-2 suggests a cannabinoid-sensitive component in the early toxicity induced by organic acids accumulating in glutaric acidemia type I and in related disorders of propionate metabolism in rat brain synaptosomes
-
Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidative Stress in Rat Brain Synaptosomes: New Converging Mechanisms
OSTEOPOROSIS/BONES and CARTILAGE (69)
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Hypothalamic regulation of bone
-
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies
-
Tissue Engineering of Cartilage, Can Cannabinoids Help?
-
Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Micro-environment
-
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss
-
CB2 Cannabinoid Receptor Targets Mitogenic Gi ProteinâCyclin D1 Axis in Osteoblasts
-
Cannabinoids and Bone: Friend or Foe?
-
Activation of cannabinoid receptor CB2 regulates osteogenic and osteoclastogenic gene expression in human periodontal ligament cells
-
The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health
-
Control of bone remodeling by nervous system. Nervous system and bone
-
Peripheral cannabinoid type 2 receptor regulates osteoclast formation, MDA-MB-231 breast cancer cell migration and bone marrow/tumour cell interaction via PI3 kinase/AKT and P38 pathways
-
Loss of the cannabinoid receptor CB2 alters the mechanical but not the material properties of bone
-
The type 2 cannabinoid receptor protects against age-related bone loss and ovariectomy induced bone loss by stimulating bone formation
-
Is lipid signaling through cannabinoid 2 receptors part of a protective system?
-
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro
-
The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation
-
Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family
-
Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators
-
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
-
The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse
-
Paracetamol (acetaminophen) use, fracture and bone mineral density
-
Expression of cannabinoid receptors by human articular chondrocytes
-
The CB2 receptor regulates osteoclast formation, breast cancer cell migration and osteoclast/tumour cell interaction via the PI3 Kinase/AKT pathway
-
Role of cannabinoids in the regulation of bone remodeling
-
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
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Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2
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THE CO-EXPRESSION OF THE ENDOCANNABINOID SYSTEM AND THE RANK/RANKL SIGNALLING PATH-WAY IN HUMAN BONE AND OSTEOCLAST CULTURE
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Cannabinoids: novel therapies for arthritis?
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Combined deficiency of the CB1 and CB2 receptors enhances peak bone mass by inhibiting osteoclast differentiation but increases age-related bone loss by promoting adipocyte differentiation and reducing osteoblast differentiation
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Magnolol Ameliorates Ligature-Induced Periodontitis in Rats and Osteoclastogenesis: In Vivo and In Vitro Study
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Cannabinoid WIN-55,212-2 Mesylate Inhibits Interleukin-1β Induced Matrix Metallo-proteinase and Tissue Inhibitor of Matrix Metalloproteinase Expression in Human Chondrocytes
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The cannabinoid receptor type 1 is essential for mesenchymal stem cell survival and differentiation: implications for bone health
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The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression
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Increase of mesenchymal stem cell migration by Cannabidiol via activation of p42/44 MAPK
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Modulation of Strain-Specific Differences in Gene Expression by Cannabinoid Type 2 Receptor Deficiency
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New insights into the physiology of bone regulation: the role of neuro-hormones
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Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels
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Therapeutical Potential of CB2 Receptors in Immune-Related Diseases
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Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC (bone mineral content)
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Type-2 cannabinoid receptor regulates proliferation, apoptosis, differentiation, and OPG / RANKL ratio of MC3T3-E1 cells exposed to Titanium particles
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Genetic background modifies the effects of type 2 cannabinoid receptor deficiency on bone mass and bone turnover
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Activation of Cannabinoid Receptor 2 Enhances Osteogenic Differentiation of Bone Marrow Derived Mesenchymal Stem Cells
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Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer induced osteolysis
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Cannabis â the Israeli perspective
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The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation
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The skeletal endocannabinoid system: clinical and experimental insights
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A synergistic interaction of 17-β-estradiol with specific cannabinoid receptor type 2 antagonist/inverse agonist on proliferation activity in primary human osteoblasts
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Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone
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Cannabidiol, a Major Non-Psychotrophic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
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CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Î9-tetrahydrocannabinol
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Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs
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Osseous Characteristics of Mice Lacking Cannabinoid Receptor 2 after Pulp Exposure
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CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity
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The brain in bone and fuel metabolism
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Effects of bioactive fatty acid amide derivatives in zebrafish scale model of bone metabolism and disease
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A collaboration investigating endocannabinoid signalling in brain and bone
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The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets
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Exploring the Bone Proteome to Help Explain Altered Bone Remodeling and Preservation of Bone Architecture and Strength in Hibernating Marmots
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Cannabinoid WIN-55,212-2 mesylate inhibits ADAMTS-4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan-1
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Anti-Inflammatory and Osteoprotective Effects of Cannabinoid-2 Receptor Agonist Hu- 308 in a Rat Model of Lipopolysaccharide-Induced Periodontitis
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Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice
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Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets
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The Central Nervous System and Bone Metabolism: An Evolving Story
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The endocannabinoid system and bone
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Overlapping molecular pathways between cannabinoid receptors type 1 and 2 and estrogens/androgens on the periphery and their involvement in the pathogenesis of common diseases (Review)
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PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity
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The role of mifamurtide in chemotherapy-induced osteoporosis of children with osteosarcoma
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Protective effects of trans-caryophyllene on maintaining osteoblast function
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β-Caryophyllene promotes osteoblastic mineralization, and suppresses osteoclastogenesis and adipogenesis in mouse bone marrow cultures in vitro
OVARIAN CYSTS (7)
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Lack of association between C385A functional polymorphism of the fatty acid amide hydrolase gene and polycystic ovary syndrome
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Relationship between leptin receptor and polycystic ovary syndrome
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Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls
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Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome
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Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome
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Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome
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Decreased expression of fatty acid amide hydrolase in women with polycystic ovary syndrome
OVERDOSE PREVENTION-OPIATE/OPIOID (9)
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Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (link to download-
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Cannabis as an adjunct to or substitute for opiates in the treatment of chronic pain
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Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal
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Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010
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The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report
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Veterans Health Administration Policy on Cannabis as an Adjunct to Pain Treatment with Opiates
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Is cannabis use associated with less opioid use among people who inject drugs?
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Medical cannabis associated with decreased opiate medication use in retrospective crosssectional survey of chronic pain patients
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Problematic Use of Prescription Opioids and Medicinal Cannabis Among Patients Suffering from Chronic Pain
OVERDOSES on CANNABINOIDS (21)
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Cannabis Overdose
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Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada)
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Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain
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Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine
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Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature
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Acute cannabis poisoning in a 10-month-old infant
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Recreational use and overdose of ingested processed cannabis (Majoon Birjandi) in the eastern Iran
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Pregnenolone can protect the brain from cannabis intoxication
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Intoxication from accidental ingestion of hashish: Analysis of eight cases
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A cannabinoid-intoxicated child treated with dexmedetomidine: a case report
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Notes from the Field: Death Following Ingestion of an Edible Marijuana Product â Colorado, March
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A non-classical cannabinoid syndrome
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Sudden onset unexplained encephalopathy in infants: think of cannabis intoxication
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Merck Manual â Marijuana (Cannabis) Professional version
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Merck Manual â Marijuana (Cannabis) Consumer version
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âThose edibles hit hardâ: Exploration of Twitter data on cannabis edibles in the U.S.
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Marijuana Misadventures in Children: Exploration of a Dose-Response Relationship and Summary of Clinical Effects and Outcomes
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Accidental cannabis poisoning in the elderly
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Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA
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Storage and disposal of medical cannabis among patients with cancer: Assessing the risk of diversion and unintentional digestion
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Tasty THC: Promises and Challenges of Cannabis Edibles
OVERVIEWS (18)
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Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada)
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Cannabis and Its Derivatives: Review of Medical Use
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Is lipid signaling through cannabinoid 2 receptors part of a protective system?
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Global Commission Drug Report
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Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed
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The endocannabinoid system: an overview
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The Therapeutic Potential of Cannabis and Cannabinoids
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Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana
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Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective
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The Legalization of Marijuana in Colorado: The Impact. Rocky Mountain HIDTA. The Impact
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Report on Medical Cannabis Research History- What the Science Says
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An Overview of Products and Bias in Research
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Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drugâs harm to children and adults, but the scientific evidence is seldom clear-cut (Part 1 of 2)
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Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2)
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Endocannabinoids
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Marijuana Legalization and Decriminalization Overview
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Cannabis in the United States
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Cannabinoids in the Brain: New Vistas on an Old Dilemma
