Medisinsk forskning på cannabis
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P
PAIN (420)
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Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain
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Endocannabinoid involvement in endometriosis
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A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss
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Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
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Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
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Historical essay: An Arabic surgeon, Ibn al Quffâs (1232-1286) account on surgical pain relief
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NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System.
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Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain
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Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia
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Dronabinol for the treatment of unspecific pain, restlessness and spasticity in neuropaediatrics
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Role of cannabinoids in the treatment of pain and (painful) spasticity
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Electroacupuncture increases CB2 receptor expression on keratinocytes and infiltrating inflammatory cells in inflamed skin tissues of rats
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Cannabinoid receptor CB1-immunoreactive nerve fibres in painful and non-painful human tooth pulp
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A catalytically silent FAAH-1 variant drives anandamide transport in neurons
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Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice
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Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats
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Cannabinoid CB2 Receptors Contribute to Upregulation of β-endorphin in Inflamed Skin Tissues by Electroacupuncture
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Is lipid signaling through cannabinoid 2 receptors part of a protective system?
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The Central Role of Glia in Pathological Pain and the Potential of Targeting the Cannabinoid 2 Receptor for Pain Relief
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Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
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Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain
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Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Î9-Tetrahydrocannabinol and CP55,940 in the Rat
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Pharmacological characterization of AM1710, a putative cannabinoid CB(2) agonist from the cannabilactone class: Antinociception without central nervous system side-effects
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Cannabinoids for Treatment of Chronic Non-Cancer Pain, a Systematic Review of Randomized Trials
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Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice
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Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness
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High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women
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Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia
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Cannabinoids attenuate cancer pain and proliferation in a mouse model
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US Patent 7884133 B2 Cannabidiol derivatives such as 3-(2,6-dihydroxy-4-pentyl-phenyl)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, used as analgesics, anti-inflammatory and antidiarrheal agents
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TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Î9-tetrahydrocannabiorcol
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The intersection between cannabis and cancer in the United States
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Role of Cannabinoids in Multiple Sclerosis
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Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (link to download-
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Treating pain in multiple sclerosis
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Effects of repeated electroacupuncture on gene expression of cannabinoid receptor-1 and dopamine 1 receptor in nucleus accumbens-caudate nucleus region in inflammatory-pain rats
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Cannabinoid-opioid interaction in chronic pain
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Antinociception and sedation following intracerebroventricular administration of Îâ¹-tetrahydrocannabinol in female vs. male rats
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Medical cannabis: the opportunity versus the temptation
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The antinociceptive potency of N-arachidonoyl-dopamine (NADA) and its interaction with endomorphin-1 at the spinal level
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A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats
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FROM GHENNAB TO CANNABIS: HOPES TO FIND A CURE FOR MULTIPLE SCLEROSIS ARE FLOURISHING
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Medical Marijuana: Clearing Away the Smoke
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The periaqueductal gray contributes to bidirectional enhancement of antinociception between morphine and cannabinoids
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Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat
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Differences in peripheral endocannabinoid modulation of scratching behavior in facial vs spinally-innervated skin
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âRedundancyâ of endocannabinoid inactivation: new challenges and opportunities for pain control
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Therapeutic modulation of cannabinoid lipid signaling: Metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist
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Clinical implications for cannabinoid use in the rheumatic diseases: potential for help or harm?
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The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level
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Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis
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Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Non-inflammatory Pain
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Cannabidiol in humans-the quest for therapeutic targets
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The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice
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The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyper-algesia in patients with neuromyelitis optica
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Neonatal DSP-4 Treatment Modifies Antinociceptive Effects of the CB(1) Receptor Agonist Methanandamide in Adult Rats
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The Therapeutic Potential of Cannabis and Cannabinoids
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Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats
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Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia
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Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy
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The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy
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Endocannabinoid modulation of jejunal afferent responses to LPS
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Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series
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Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters â A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs
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Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide
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Monoacylglycerol lipase â a target for drug development?
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Intrathecal cannabilactone CB(2)R agonist, AM1710, controls pathological pain and restores basal cytokine levels
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
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Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
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Cannabinoids and muscular pain. Effectiveness of the local administration in rat
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Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2
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Cannabinergic Pain Medicine: A Concise Clinical Primer and Survey of Randomized controlled Trial Results
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Anandamide and 2-arachidonoylglycerol: Pharmacological Properties, Functional Features and Emerging Specificities of the Two Major Endocannabinoids
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The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke
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Role of cannabinoid 2 receptor in the development of bone cancer pain
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Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial
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Metamizol, a non-opioid analgesic, acts via endocannabinoids in the PAG-RVM axis during inflammation in rats
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The interaction between intrathecal administration of low doses of palmitoylethanolamide and AM251 in formalin-induced pain related behavior and spinal cord IL1-β expression in rats
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Acute Reduction of Anandamide-Hydrolase (FAAH) Activity is Coupled With a Reduction of Nociceptive Pathways Facilitation in Medication-Overuse Headache Subjects After Withdrawal Treatment
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Analgesic effects of cannabinoids on central pain syndrome
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Cannabis as an adjunct to or substitute for opiates in the treatment of chronic pain
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Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
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Effects of dronabinol on morphine-induced dopamine-related behavioral effects in animals
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Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception
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Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors
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Palmitoylethanolamide versus a nonsteroidal anti-inflammatory drug in the treatment of temporomandibular joint inflammatory pain
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Interactions between mu opioid receptor agonists and cannabinoid receptor agonists in rhesus monkeys: antinociception, drug discrimination, and drug self-administration
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Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury
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Differential modulation of nociceptive versus non-nociceptive synapses by endocannabinoids
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The Major Brain Endocannabinoid 2-AG Controls Neuropathic Pain and Mechanical Hyperalgesia in Patients with Neuromyelitis Optica
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Role of endogenous cannabinoid system in the gut
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Treatment of chronic regional pain syndrome type 1 with palmitoylethanolamide and topical ketamine cream: modulation of nonneuronal cells
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The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model
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Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint
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The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain
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Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist
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On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation
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The endocannabinoid system, cannabinoids, and pain
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Cannabinoid receptors and pain
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Amygdala activity contributes to the dissociative effect of cannabis on pain perception
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Dissociation of the Pharmacological Effects of THC by mTOR Blockade
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Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract
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CB1 and CB2 Cannabinoid Receptor Agonists Induce Peripheral Antinociception by Activation of the Endogenous Noradrenergic System
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Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects
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The cannabinoid-1 receptor inverse agonist taranabant reduces abdominal pain and increases intestinal transit in mice
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The non-selective cannabinoid receptor agonist WIN 55,212-2 attenuates responses of Cfiber nociceptors in a murine model of cancer pain
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The role of androgen receptor in transcriptional modulation of cannabinoid receptor type 1 gene in rat trigeminal ganglia
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CB1 Cannabinoid Receptor Agonist Prevents NGF-Induced Sensitization of TRPV1 in Sensory Neurons
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Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana In Daily Marijuana Smokers
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The Subjective Psychoactive Effects of Oral Dronabinol Studied in a Randomized, Controlled Crossover Clinical Trial For Pain
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Targeting the cannabinoid system for pain relief?
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The Medical Necessity for Medicinal Cannabis: Prospective, Observational Study Evaluating the Treatment in Cancer Patients on Supportive or Palliative Care
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The use of cannabinoids in chronic pain
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Endocannabinoid and cannabinoid-like fatty acid amide levels correlate with pain-related symptoms in patients with IBS-D and IBS-C: a pilot study
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β-Arrestins: Regulatory Role and Therapeutic Potential in Opioid and Cannabinoid Receptor-Mediated Analgesia
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Different Classes of CB2 Ligands Potentially Useful in the Treatment of Pain
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The role of endocannabinoids in pain modulation
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Interactions between mu opioid receptor agonists and cannabinoid receptor agonists CP55940 and WIN55212-2 in rhesus monkeys: evaluation of treatment- and abuserelated effects
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Antinociceptive effects of the selective CB2 agonist MT178 in inflammatory and chronic rodent pain models
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Involvement of the opioid and cannabinoid systems in pain control: new insights from knockout studies
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Endocannabinoids: A unique opportunity to develop multitarget analgesics
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Adolescent peer-rejection persistently alters pain perception and CB1 receptor expression in female rats
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Effects of the cannabinoid 2 receptor-selective agonist GW405833 in assays of acute pain-stimulated and paindepressed behavior in rats
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Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists
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Sex differences in anti-allodynic, anti-hyperalgesic and anti-edema effects of Î9-tetrahydrocannabinol in the rat
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CB1 and CB2 contribute to antinociceptive and anti-inflammatory effects of electro-acupuncture on experimental arthritis of the rat temporomandibular joint
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Administration of micronized palmitoylethanolamide (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results
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Pharmacology of Cannabinoid Receptor Agonists and a Cyclooxygenase-2 Inhibitor in Rat Bone Tumor Pain
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Involvement of cannabinoid CB1 receptors in the antinociceptive effect of dipyrone
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Palmitoylethanolamide and stearoylethanolamide levels in the interstitium of the trapezius muscle of women with chronic widespread pain and chronic neck-shoulder pain correlate with pain intensity and sensitivity
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Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons
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Peripheral and Spinal Activation of Cannabinoid Receptors by Joint Mobilization Alleviates Postoperative Pain in Mice
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The endocannabinoid system mediates aerobic exercise-induced antinociception in rats
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The adjuvant use of N-palmitoylethanolamine and transpolydatin in the treatment of endometriotic pain
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Endocannabinoids: a unique opportunity to develop multitarget analgesics
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Postoperative Analgesia in the Jamaican Cannabis User
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New insights in mast cell modulation by palmitoylethanolamide
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Non-neuronal cell modulation relieves neuropathic pain: efficacy of the endogenous lipid palmitoylethanolamide
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Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation
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Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists
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A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain
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Inhibition of Fatty Acid binding proteins elevates brain anandamide levels and produces analgesia
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The consequences of pain in early life: injury-induced plasticity in developing pain pathways
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CB2 cannabinoid receptors as a therapeutic target â What does the future hold?
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Systematic review: Efficacy and safety of medical marijuana in selected neurologic disorders: Report of the Guideline Development Subcommittee of the American Academy of Neurology
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Therapeutic benefits of cannabis: a patient survey
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Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia
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Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice
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Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord
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Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery
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R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice
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Impact of efficacy at the mu opioid receptor on antinociceptive effects of combinations of mu opioid receptor agonists and cannabinoid receptor agonists
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Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol / high fat diet induced pancreatitis
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NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors
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Celastrol Attenuates Inflammatory and Neuropathic Pain Mediated by Cannabinoid Receptor Type 2
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Therapeutic Potential of Inhibitors of Endocannabinoid Degradation for the Treatment of Stress-Related Hyperalgesia in an Animal Model of Chronic Pain
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Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints
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CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model
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Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and paindepressed behavior in rats
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TRP channel cannabinoid receptors in skin sensation, homeostasis, and inflammation
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Complementary and alternative medical therapies in multiple sclerosis-the american academy of neurology guidelines: a commentary
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Use of a Synthetic Cannabinoid in a Correctional Population for Posttraumatic Stress Disorder-Related Insomnia and Nightmares, Chronic Pain, Harm Reduction, and Other Indications: A Retrospective Evaluation
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A lipid gate for the peripheral control of pain
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Endocannabinoid system and pain: an introduction
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Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine
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The cannabinoid CBâ receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain
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Acute Resistance Exercise Induces Antinociception by Activation of the Endo-cannabinoid System in Rats
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Sex differences in antinociceptive tolerance to delta-9-tetrahydrocannabinol in the rat
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Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides
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Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not âhigherâ
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Epigenetic Regulation of Genes that Modulate Chronic Stress-induced Visceral Pain in the Peripheral Nervous System
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Mechanisms of Exercise-Induced Hypoalgesia
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Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models
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Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
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Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey
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Activation of CB1 inhibits NGF-induced sensitization of TRPV1 in adult mouse afferent neurons
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The analgesic effect of dipyrone in peripheral tissue involves two different mechanisms: Neuronal KATP channel opening and CB1 receptor activation
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Effects of Two Different Specific Neck Exercise Interventions on Palmitoylethanolamide and Stearoylethanolamide Concentrations in the Interstitium of the Trapezius Muscle in Women with Chronic Neck Shoulder Pain
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Attenuation of Cystitis and Pain Sensation in Mice Lacking Fatty Acid Amide Hydrolase.
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Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury
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The Medicinal Cannabis Treatment Agreement: Providing Information to Chronic Pain Patients via a Written Document
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The Neurobiology of Cancer Pain
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Intraganglionic injection of a nitric oxide donator induces afferent mechanical sensitization that is attenuated by palmitoylethanolamide
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Cannabinoid Receptor Type 1 Antagonist, AM251, Attenuates Mechanical Allodynia and Thermal Hyperalgesia after Burn Injury
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The Comprehensive Report on the Cannabis Extract Movement and the Use of Cannabis Extracts to Treat Diseases (link to download-
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Report on Medical Cannabis Research History- What the Science Says
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The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice
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Peripheral neurobiologic mechanisms of antiallodynic effect of warm water immersion therapy on persistent inflammatory pain
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Involvement of the endocannabinoid system in osteoarthritis pain
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Therapeutic Potential of Cannabinoids in Counteracting Chemotherapy-induced Adverse Effects: An Exploratory Review
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Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state
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Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling
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Anandamide in primary sensory neurons: too much of a good thing?
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Therapeutic Satisfaction and Subjective Effects of Different Strains of Pharmaceutical Grade Cannabis
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Inhibition of Voltage-Gated Na+ Channels by the Synthetic Cannabinoid Ajulemic Acid
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Vagal anandamide signaling via cannabinoid receptor 1 contributes to luminal 5-HT modulation of visceral nociception in rats
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Dronabinol and chronic pain: importance of mechanistic considerations
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Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol
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Cyclic ovarian hormone modulation of supraspinal Î9-tetrahydrocannabinol-induced antinociception and cannabinoid receptor binding in the female rat
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Analgesic tolerance and cross-tolerance to the cannabinoid receptors ligands hemopressin, VD-hemopressin(α) and WIN55,212-2 at the supraspinal level in mice
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Effects of opioids and cannabinoids during chronic morphine treatment in rhesus monkeys
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Descending modulation of pain: the GABA disinhibition hypothesis of analgesia
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Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue
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Cannabidiol and endogenous opioid peptide-mediated mechanisms modulate anti-nociception induced by transcutaneous electrostimulation of the peripheral nervous system
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Colitis generates remote antinociception in rats: the role of the Larginine/NO/cGMP/ PKG/KATP pathway and involvement of cannabinoid and opioid systems
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Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users
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Evaluation of the tolerability and efficacy of Sativex in multiple sclerosis
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Interaction of a Cannabinoid-2 Agonist With Tramadol on Nociceptive Thresholds and Immune Responses in a Rat Model of Incisional Pain
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Involvement of central and peripheral cannabinoid receptors on antinociceptive effect of tetrahydrocannabinol in muscle pain
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Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain
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Involvement of the endocannabinoid system in attentional modulation of nociceptive behaviour in rats
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Potential applications of marijuana and cannabinoids in medicine
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Experience of adjunctive cannabis use for chronic non-cancer pain: Findings from the Pain and Opioids IN Treatment (POINT) study
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Re-branding cannabis: the next generation of chronic pain medicine?
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Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases
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Distinct interactions of cannabidiol and morphine in three nociceptive behavioral models in mice
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Cannabis use provides symptom relief in patients with inflammatory bowel disease but is associated with worse disease prognosis in patients with Crohnâs disease
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Selective monoacylglycerol lipase inhibitors: Antinociceptive vs. cannabimimetic effects in mice
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The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Peri-aqueduactal Grey
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Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice
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Use of Prescription Pain Medications Among Medical Cannabis Patients: Comparisons of Pain Levels, Functioning, and Patterns of Alcohol and Other Drug Use
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Intrathecal cannabinoid-1 receptor agonist prevents referred hyperalgesia in acute acrolein-induced cystitis in rats
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Cannabis in cancer care
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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
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Coadministration of indomethacin and minocycline attenuates established paclitaxel induced neuropathic thermal hyperalgesia: Involvement of cannabinoid CB1 receptors
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A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome
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Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors
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Cannabis and Cannabinoidsâfor health professionals (PDQ®)
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Cannabis and Cannabinoids (PDQ®): Patient Version
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High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity
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The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons
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Efficacy and adverse effects of medical marijuana for chronic noncancer pain: Systematic review of randomized controlled trials
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Prevalence and determinants of cannabinoid prescription for the management of chronic noncancer pain: a postal survey of physicians in the Abitibi-Témiscamingue region of Quebec
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Cannabinoids for Medical Use A Systematic Review and Meta-analysis
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Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid / N-acylethanolamine-dependent mechanisms
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TRPV1 channel inhibition contributes to the antinociceptive effects of Croton macrostachyus extract in mice
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Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
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Systematic Review of the Use of Phytochemicals for Management of Pain in Cancer Therapy
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Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
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Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
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Cannabinoids for Medical Use: A Systematic Review and Meta-analysis
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Prevalence and determinants of cannabinoid prescription for the management of chronic noncancer pain: a postal survey of physicians in the Abitibi-Témiscamingue region of Quebec
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Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency
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Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency
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Endocannabinoids and acute pain after total knee arthroplasty
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Endocannabinoids and acute pain after total knee arthroplasty
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Cannabinoids in the management of chronic pain: a front line clinical perspective
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Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain
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Patterns of Use of Medical Cannabis Among Israeli Cancer Patients: A Single Institution Experience
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Gonadal hormones do not alter the development of antinociceptive tolerance to delta-9-tetrahydrocannabinol in adult rats
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Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review
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Medical Marijuana: Is the Cart Before the Horse?
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Sequelae of Cannabis as Medicine
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Anandamide Depresses Glycinergic and GABAergic Inhibitory Transmissions in Adult Rat Substantia Gelatinosa Neurons
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Use of paracetamol during pregnancy and child neurological development
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Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy
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Fatty acid amide hydrolase inhibitors: a patent review (2009-
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Clinical perspectives on medical marijuana (cannabis) for neurologic disorders
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The modulatory effect of anandamide on nitroglycerin-induced sensitization in the trigeminal system of the rat
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The modulatory effect of anandamide on nitroglycerin-induced sensitization in the trigeminal system of the rat
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Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress
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The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report
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The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation: a case report
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The effect of FAAH, MAGL, and Dual FAAH/MAGL inhibition on inflammatory and colorectal distension-induced visceral pain models in Rodents
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The effect of FAAH, MAGL, and Dual FAAH/MAGL inhibition on inflammatory and colorectal distension-induced visceral pain models in Rodents
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The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats
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The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats. (link to
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Tonic Modulation of Nociceptive Behavior and Allodynia by Cannabinoid Receptors in Formalin Test in Rats
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Tonic Modulation of Nociceptive Behavior and Allodynia by Cannabinoid Receptors in Formalin Test in Rats (click âFull Text Linksâ for PDF-
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Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS)
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Cannabinoid receptor-specific mechanisms to ameliorate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation
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Acupuncture Mechanisms: Anesthesia, Analgesia and Protection on Organ Functions
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Veterans Health Administration Policy on Cannabis as an Adjunct to Pain Treatment with Opiates
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Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2)
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The entourage effect: Synergistic actions of plant cannabinoids
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Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials
-
Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials
-
The Effectiveness of Cannabinoids in the Management of Chronic Nonmalignant Neuro-pathic Pain: A Systematic Review
-
Acute administration of a cannabinoid CB1 receptor antagonist impairs stress-induced antinociception in fish
-
Peripherally Restricted Cannabinoids for the Treatment of Pain
-
Profiles of medicinal cannabis patients attending compassion centers in rhode island
-
The role of cannabinoids in regulation of nausea and vomiting, and visceral pain
-
Cannabinoid CB1 receptors mediate the effects of dipyrone
-
Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-endoccannabinoid receptor in the ventral mesencephalon
-
The role of the endocannabinoid system in pain
-
Emerging concepts of pain therapy based on neuronal mechanisms
-
Repeated forced swim stress differentially affects formalin-evoked nociceptive behaviour and the endocannabinoid system in stress normo-responsive and stress hyper-responsive rat strains
-
Lipid nanoparticles as an emerging platform for cannabinoid delivery: physicochemical optimization and biocompatibility
-
Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release
-
Modulatory effects by CB1 receptors on rat spinal locomotor networks after sustained application of agonists or antagonists
-
Retrospective Analysis of Tetrahydrocannabinol Based on 31 Neurologically Critically Ill Children
-
Cross-tolerance to cannabinoids in morphine-tolerant rhesus monkeys
-
Microinjection of orexin-A into the rat locus coeruleus nucleus induces analgesia via cannabinoid type-1 receptors
-
Clinical pharmacology of medical cannabinoids in chronic pain
-
Neuropeptide VF Enhances Cannabinoid Agonist WIN55,212-2-Induced Antinociception in Mice
-
A 4-Week Pilot Study With the Cannabinoid Receptor Agonist Dronabinol and Its Effect on Metabolic Parameters in a Randomized Trial
-
Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence
-
Chronic stress and peripheral pain: Evidence for distinct, region-specific changes in visceral and somatosensory pain regulatory pathways
-
The Efficacy of Eslicarbazepine Acetate in Models of Trigeminal, Neuropathic, and Visceral Pain: The Involvement of 5-HT1B/1D Serotonergic and CB1/CB2 Cannabinoid Receptors
-
A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation
-
Brain Mapping-Based Model of Î9-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix
-
Receptome: Interactions between three pain-related receptors or the âTriumvirateâ of cannabinoid, opioid and TRPV1 receptors
-
The long-term functional consequences of acute infectious diarrhea
-
The Role of the Brainâs Endocannabinoid System in Pain and Its Modulation by Stress
-
Use of Cannabinoids for Spasticity and Pain Management in MS
-
Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression in Walker 256 Tumor-Bearing Rats
-
Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice
-
Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release
-
Analysis of the anti-allodynic effects of combination of a synthetic cannabinoid and a selective noradrenaline re-uptake inhibitor in nerve injury-induced neuropathic mice
-
Combined Treatment with Morphine and Î9-Tetrahydrocannibinol (THC) in Rhesus Monkeys: Antinociceptive Tolerance and Withdrawal
-
β-caryophyllene-complexed in β-cyclodextrin Produces Antihyperalgesic Activity in Animal Model for Fibromyalgia
-
Efficacy and safety of nabiximols (Sativex®) on multiple sclerosis spasticity in a real-life Italian monocentric study
-
Intrathecal Injection of JWH-015 Attenuates Bone Cancer Pain Via Time-Dependent Modification of Pro-inflammatory Cytokines Expression and Astrocytes Activity in Spinal Cord
-
Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence
-
Is cannabis use associated with less opioid use among people who inject drugs?
-
Up-regulation of immunomodulatory effects of mouse bone-marrow derived mesenchymal stem cells by tetrahydrocannabinol pre-treatment involving cannabinoid receptor CB2
-
Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing Remitting Multiple Sclerosis
-
δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats
-
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase
-
Endovanilloids are potential activators of the trigeminovascular nocisensor complex
-
Cannabinoid 1 receptor knockout mice display cold allodynia, but enhanced recovery from spared-nerve injury-induced mechanical hypersensitivity
-
Tolerance to the diuretic effects of cannabinoids and cross-tolerance to a kappa-opioid agonist in THC-treated mice
-
Interactions between cannabinoid receptor agonists and mu opioid receptor agonists in rhesus monkeys discriminating fentanyl
-
Cannabinoid pharmacology in cancer research: A new hope for cancer patients?
-
Expression of the endocannabinoid receptors in human fascial tissue
-
Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems-A Novel Treatment Option for Chronic Pain Management
-
Turning Down the Thermostat: Modulating the Endocannabinoid System in Ocular Inflammation and Pain
-
Cannabinoid Buccal Spray for Chronic Non-Cancer or Neuropathic Pain: A Review of Clinical Effectiveness, Safety, and Guidelines
-
Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling
-
Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation
-
Paracetamol sharpens reflection and spatial memory: a double-blind randomized controlled study in healthy volunteers
-
Rescue of Impaired mGluR5-Driven Endocannabinoid Signaling Restores Prefrontal Cortical Output to Inhibit Pain in Arthritic Rats
-
A spider derived peptide, PnPP-19, induces central antinociception mediated by opioid and cannabinoid systems
-
A userâs guide to cannabinoid therapies in oncology
-
Marijuana Compounds: A Nonconventional Approach to Parkinsonâs Disease Therapy
-
Dissecting the signaling pathways involved in the crosstalk between mGlu5 and CB1 receptors
-
Endocannabinoid system: Role in depression, reward and pain control (Review)
-
Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
-
Behavioral Characterization of Kappa Opioid Receptor Agonist Spiradoline and Cannabinoid Receptor Agonist CP55940 Mixtures in Rats (link to
-
Using Medical Cannabis in an Oncology Practice
-
Using Medical Cannabis in an Oncology Practice
-
Opioids Out, Cannabis In
-
Cannabis and Cannabinoids.
-
Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord
-
Medical use of cannabis products : Lessons to be learned from Israel and Canada
-
Effect of JWH-250, JWH-073 and their interaction on âtetradâ, sensorimotor, neuro-logical and neurochemical responses in mice
-
Quantification of pain in sickle mice using facial expressions and body measurements
-
CB1 Cannabinoid Agonist (WIN55,212-2) Within the Basolateral Amygdala Induced Sensitization to Morphine and Increased the Level of μ-Opioid Receptor and c-fos in the Nucleus Accumbens
-
Efficacy, tolerability, and safety of cannabinoids in gastroenterology : A systematic review
-
RGS proteins as targets in the treatment of intestinal inflammation and visceral pain: New insights and future perspectives
-
Effect of endocannabinoid degradation on pain: role of FAAH polymorphisms in experimental and postoperative pain in women treated for breast cancer
-
Dronabinol increases pain threshold in patients with functional chest pain: a pilot doubleblind placebo-controlled trial
-
Medical cannabis: considerations for the anesthesiologist and pain physician
-
β-caryophyllene, a dietary cannabinoid, complexed with β-cyclodextrin produced antihyperalgesic effect involving the inhibition of Fos expression in superficial dorsal horn
-
Development and Pharmacological Characterization of Selective Blockers of 2- Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
-
Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray
-
Cannabinoids: Medical implications
-
Nabilone for the Management of Pain
-
A Single Intrathecal or Intraperitoneal Injection of CB2 Receptor Agonist Attenuates Bone Cancer Pain and Induces a Time-Dependent Modification of GRK2
-
Role of cannabinoids in gastrointestinal mucosal defense and inflammation
-
Combined treatment with morphine and Î9-tetrahydrocannibinol (THC) in rhesus monkeys: antinociceptive tolerance and withdrawal
-
Effects of cannabinoid receptor activation by CP55,940 on normal bladder function and irritation-induced bladder overactivity in non-awake anaesthetised rats
-
Sickle Cell Crisis Complicated by Synthetic Cannabinoid Abuse: A Case Report
-
Cannabis in Pain Treatment: Clinical & Research Considerations
-
The Effect of Medicinal Cannabis on Pain and Quality of Life Outcomes in Chronic Pain: A Prospective Open-label Study
-
Rational Basis for the Use of Bergamot Essential Oil in Complementary Medicine to Treat Chronic Pain
-
Medical cannabis associated with decreased opiate medication use in retrospective crosssectional survey of chronic pain patients
-
Mesoporous Silica Particles as a Multifunctional Delivery System for Pain Relief in Experimental Neuropathy
-
Piperidinyl thiazole isoxazolines: A new series of highly potent, slowly reversible FAAH inhibitors with analgesic properties
-
Adolescent social rejection alters pain processing in a CB1 receptor dependent manner
-
Pain, Cannabis Species, and Cannabis Use Disorders
-
MEDICAL CANNABIS
-
Differences in Chloride Gradients Allow for Three Distinct Types of Synaptic Modulation by Endocannabinoids
-
TRPV1-FAAH-COX: The Couples Game in Pain Treatment
-
Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review
-
Transmission Pathways and Mediators as the Basis for Clinical Pharmacology of Pain
-
The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain
-
PnPP-19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase
-
An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain from Spinal Cord Injury and Disease
-
Problematic Use of Prescription Opioids and Medicinal Cannabis Among Patients Suffering from Chronic Pain
-
New Zealand Health Survey 2012/13: characteristics of medicinal cannabis users
-
Changes in nociceptin/orphanin FQ levels in rat brain regions after acute and chronic cannabinoid treatment in conjunction with the development of antinociceptive tolerance
-
Inhibitors of diacylglycerol lipases in neurodegenerative and metabolic disorders
-
Refractory trigeminal neuralgia responsive to nabiximols in a patient with multiple sclerosis
-
Peripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia
-
Factors associated with having a medical marijuana card among Veterans with recent substance use in VA outpatient treatment
-
Endocannabinoids control vesicle release mode at midbrain periaqueductal grey inhibitory synapses
-
The Effect of Muscarinic Receptor Modulators on the Antinociception Induced by CB2 Receptor Agonist, JWH133 in Mice
-
Robust anti-nociceptive effects of MAG lipase inhibition in a model of osteoarthritis pain
-
Sex-dependent effects of cannabis-induced analgesia
-
Endocannabinoid mechanism for orofacial antinociception induced by electroacupuncture in acupoint St36 in rats
-
Peltatoside Isolated from Annona crassiflora Induces Peripheral Antinociception by Activation of the Cannabinoid System
-
Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation
-
Pain in Extrapyramidal Neurodegenerative Diseases
-
N-palmitoylethanolamide in the anterior cingulate cortex attenuates inflammatory pain behaviour indirectly via a CB1 receptor-mediated mechanism
-
Gonadal hormone modulation of â9-tetrahydrocannabinol-induced antinociception and metabolism in female versus male rats
-
Efficacy, tolerability, and safety of cannabinoids in gastroenterology: A systematic review
-
Nature of the placebo and nocebo effect in relation to functional neurologic disorders
-
Effect of medical cannabis on thermal quantitative measurements of pain in patients with Parkinsonâs disease
-
Therapeutic potential of fatty acid amide hydrolase, monoacylglycerol lipase, and Nacylethanolamine acid amidase inhibitors
-
Role of cannabis in digestive disorders
-
Pros and cons of medical cannabis use by people with chronic brain disorders
-
Medical Marijuana: Just the Beginning of a Long, Strange Trip?
-
Cannabinoids in the Management of Musculoskeletal or Rheumatic Diseases
-
Antagonism of cannabinoid receptor 1 attenuates the anti-inflammatory effects of electroacupuncture in a rodent model of migraine
-
Cannabinoid receptor ligand bias: implications in the central nervous system
-
The central cannabinoid receptor type-2 (CB2) and chronic pain
-
State of the evidence: Cannabinoids and cancer pain-A systematic review
-
The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice
-
A novel inhibitor of endocannabinoid catabolic enzymes sheds light on behind the scene interplay between chronic pain, analgesic tolerance, and heroin dependence
-
Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis
-
Pain in amyotrophic lateral sclerosis
-
Inflammation of peripheral tissues and injury to peripheral nerves induce diferring effects in the expression of the calcium-sensitive anandamide-synthesising enzyme and related molecules in rat primary sensory neurons
-
Expertsâ Perspectives on the Role of Medical Marijuana in Oncology: a semi-structured interview study
-
Cannabis use in persons with traumatic spinal cord injury in Denmark
-
Medical Cannabis in the Palliation of Malignant WoundsâA Case Report
-
Compensatory Activation of Cannabinoid CB2 Receptor Inhibition of GABA Release in the Rostral Ventromedial Medulla in Inflammatory Pain
-
Role of cannabis in digestive disorders
-
Antihyperalgesic effect of CB1 receptor activation involves the modulation of P2X3 receptor in the primary afferent neuron
PANCREAS/PANCREATITIS (39)
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Expression and function of cannabinoid receptors in mouse islets
-
Cannabinoid Receptors are Coupled to Stimulation of Insulin Secretion from Mouse MIN6 β-cells
-
Cannabinoid agonist WIN55,212 in vitro inhibits interleukin-6 (IL-6) and monocyte chemo-attractant protein-1 (MCP-1) release by rat pancreatic acini and in vivo induces dual effects on the course of acute pancreatitis
-
G1359A polymorphism of the cannabinoid receptor gene (CNR1) and clinical results of biliopancreatic diversion
-
The role of small molecule GPR119 agonist, AS1535907, in glucose-stimulated insulin secretion and pancreatic β-cell function
-
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells
-
Gut feelings about the endocannabinoid system
-
The role of the endocannabinoid system in islet biology
-
The CB-1 Receptor Antagonist Rimonabant Modulates the Interaction Between Adipocytes and Pancreatic Beta-Cells in Vitro
-
Cannabinoid HU210 Protects Isolated Rat Stomach against Impairment Caused by Serum of Rats with Experimental Acute Pancreatitis
-
Activation of Cannabinoid Receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms
-
Expression and function of monoacylglycerol lipase in mouse β-cells and human islets of Langerhans
-
Islet protection and amelioration of diabetes type 2 in Psammomys obesus by treatment with cannabidiol
-
Effects of CP 55,940âagonist of CB1 cannabinoid receptors on ghrelin and somatostatin producing cells in the rat pancreas
-
Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model
-
Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis
-
Cannabinoid HU210 Protects Isolated Rat Stomach against Impairment Caused by Serum of Rats with Experimental Acute Pancreatitis
-
Islet cannabinoid receptors: cellular distribution and biological function
-
Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
-
Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol / high fat diet induced pancreatitis
-
A novel GPR40 agonist, CNX-011-67, suppresses glucagon secretion in pancreatic islets under chronic glucolipotoxic conditions in vitro
-
Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function
-
A Role for Trans-caryophyllene in the Moderation of Insulin Secretion
-
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Î9 -THC
-
Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons
-
Cannabinoid CB1 receptors and mTORC1 signalling pathway interact to modulate glucose homeostasis
-
Role of the Endocannabinoid System in Diabetes and Diabetic Complications
-
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture
-
Food Liking Enhances the Plasma Response of 2-Arachidonoylglycerol and of Pancreatic Polypeptide upon Modified Sham Feeding in Humans
-
Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells
-
Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells
-
β-Caryophyllene, a natural sesquiterpene lactone attenuates hyperglycemia mediated oxidative and inflammatory stress in experimental diabetic rats
-
Efficacy, tolerability, and safety of cannabinoids in gastroenterology : A systematic review
-
GPR55-dependent stimulation of insulin secretion from isolated mouse and human islets of Langerhans
-
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, PlaceboControlled, Parallel Group Pilot Study
-
Efficacy, tolerability, and safety of cannabinoids in gastroenterology: A systematic review
-
Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes
-
Role of cannabis in digestive disorders
-
Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type-2 Diabetes
PARKINSONâS DISEASE (93)
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CannabinoidâDopamine Interaction in the Pathophysiology and Treatment of CNS Disorders
-
Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality
-
Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinsonâs disease in the rat
-
Cannabinoids and Dementia: A Review of Clinical and Preclinical Data
-
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats
-
In vivo type 1 cannabinoid receptor mapping in the 6-hydroxydopamine lesion rat model of Parkinsonâs disease
-
Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction
-
Is lipid signaling through cannabinoid 2 receptors part of a protective system?
-
Prospects for cannabinoid therapies in basal ganglia disorders
-
Symptom-relieving and neuroprotective effects of the phytocannabinoid D(9) -THCV in animal models of Parkinsonâs disease
-
Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation
-
Cannabinoid receptor signalling in neurodegenerative diseases: a potential role for membrane fluidity disturbance
-
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuro-inflammation
-
Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsonâs Disease
-
Regional changes in type 1 cannabinoid receptor availability in Parkinsonâs disease in vivo
-
Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease
-
Homeostatic changes of the endocannabinoid system in Parkinsonâs disease
-
Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors
-
The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription
-
The Therapeutic Potential of Cannabis and Cannabinoids
-
Cannabinoid modulation of neuroinflammatory disorders
-
Review article: The endocannabinoid system in normal and pathological brain ageing
-
The cannabinoid agonist WIN55212-2 decreases l-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated rats
-
Cannabinoids and value-based decision making: implications for neurodegenerative disorders
-
The decrease of dopamine D(2)/D(3) receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB(1) cannabinoid receptors in Parkinsonâs disease: A preliminary autoradiographic study with the selective dopamine D(2)/D(3) antagonist [(3)H]raclopride and the novel CB(1) inverse agonist [(125)I]SD7015
-
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
-
Î(9)-THC exerts a direct neuroprotective effect in a human cell culture model of Parkinsonâs disease
-
Contribution of genetic variants to pain susceptibility in Parkinson disease
-
Contribution of genetic variants to pain susceptibility in Parkinson disease
-
Evaluation of the role of striatal cannabinoid CB1 receptors on movement activity of parkinsonian rats induced by reserpine
-
Striatal Molecular Signature of Subchronic Subthalamic Nucleus High Frequency Stimulation in Parkinsonian Rat
-
Temporal changes of CB1 cannabinoid receptor in the basal ganglia as a possible structure-specific plasticity process in 6-OHDA lesioned rats
-
The Influence of Cannabinoids on Generic Traits of Neurodegeneration
-
Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptors activation in mice
-
A spontaneous deletion of α-Synuclein is associated with an increase in CB1 mRNA transcript and receptor expression in the hippocampus and amygdala: Effects on alcohol consumption
-
Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy
-
Therapeutic Potential of Cannabinoids in Neurodegenerative Disorders: A Selective Review
-
Î9-Tetrahydrocannabinol is protective through PPARγ dependent mitochondrial biogenesis in a cell culture model of Parkinsonâs Disease
-
Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson´s disease
-
The combination of oral L-DOPA/rimonabant for effective dyskinesia treatment and cytological preservation in a rat model of Parkinsonâs disease and L-DOPA-induced dyskinesia
-
L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus
-
The endocannabinoid system: a putative role in neurodegenerative diseases
-
The CB1 cannabinoid receptor agonist reduces L-DOPA-induced motor fluctuation and ERK1/2 phosphorylation in 6-OHDA-lesioned rats
-
Endocannabinoid signalling and the deteriorating brain
-
Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases
-
Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats
-
Effects of cannabidiol in the treatment of patients with Parkinsonâs disease: An exploratory double-blind trial
-
Report on Medical Cannabis Research, What the Science Says
-
L-DOPA disrupts adenosine A2A-cannabinoid CB1-dopamine D2 receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: Biochemical and behavioral studies
-
Cannabidiol Normalizes Capase 3, Synatophsin, and Mitochondrial Fission Protein DNM1L Expression Levels in Rats with Brain Iron Overload: Implications for Neuro-protection
-
Genome-wide microarray analysis identifies a potential role for striatal retrograde endocannabinoid signaling in the pathogenesis of experimental L-DOPA-induced dyskinesia
-
Cannabis (Medical Marijuana) Treatment for Motor and Non-Motor Symptoms of Parkinson Disease: An Open-Label Observational Study
-
Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinsonâs disease patients: a case series
-
The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model
-
Identification of CB2 receptors in human nigral neurons that degenerate in Parkinsonâs disease
-
Self-Reported Efficacy of Cannabis and Other Complementary Medicine Modalities by Parkinsonâs Disease Patients in Colorado
-
Promising cannabinoid-based therapies for Parkinsonâs disease: motor symptoms to neuroprotection
-
Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control
-
Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinsonâs disease
-
Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinsonâs disease
-
The therapeutic potential of cannabinoids for movement disorders
-
Endocannabinoid Signaling in Motivation, Reward, and Addiction: Influences on Mesocorticolimbic Dopamine Function
-
Cannabinoid-dopamine interactions in the physiology and physiopathology of the basal ganglia
-
Cannabinoids and Tremor Induced by Motor-related Disorders: Friend or Foe?
-
Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications
-
Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism
-
Potential of the cannabinoid CB2 receptor as a pharmacological target against inflammation in Parkinsonâs disease
-
The role of cannabinoids and leptin in neurological diseases
-
Differential upregulation of the cannabinoid CB2 receptor in neurotoxic and inflammation-driven rat models of Parkinsonâs disease
-
Neuroprotective Effect of JZL184 in MPP+-Treated SH-SY5Y Cells Through CB 2 Receptors
-
N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution
-
Cannabinoids for the Treatment of Movement Disorders
-
Endocannabinoids and Neurodegenerative Disorders: Parkinsonâs Disease, Huntingtonâs Chorea, Alzheimerâs Disease, and Others
-
Dopamine-dependent CB1 receptor dysfunction at corticostriatal synapses in homozygous PINK1 knockout mice
-
The neuroprotection of cannabidiol against MPP+-induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis and might be relevant to Parkinsonâs disease
-
Modulation of cellular redox homeostasis by the endocannabinoid system
-
Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis
-
Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats
-
Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinsonâs Disease
-
CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinsonâs disease
-
Marijuana Compounds: A Nonconventional Approach to Parkinsonâs Disease Therapy
-
Targeting the cannabinoid CB2 receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice
-
Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6- hydroxydopamine lesioned rat brains
-
Upregulation of the cannabinoid CB2 receptor in environmental and viral inflammation driven rat models of Parkinsonâs disease
-
Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinsons disease
-
Endocannabionoid System in Neurological Disorders
-
The bright side of psychoactive substances: cannabinoid-based drugs in motor diseases
-
Co-administration of cannabidiol and capsazepine reduces L-DOPA-induced dyskinesia in mice: Possible mechanism of action
-
Type-2 cannabinoid receptors in neurodegeneration
-
Nature of the placebo and nocebo effect in relation to functional neurologic disorders
-
Effect of medical cannabis on thermal quantitative measurements of pain in patients with Parkinsonâs disease
-
Pros and cons of medical cannabis use by people with chronic brain disorders
-
Effect of inhibition of fatty acid amide hydrolase on MPTP-induced dopaminergic neuronal damage
PATENTS RELATED TO CANNABIS (35)
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US Patent 7674922 B2 Process for production of delta-9-tetrahydrocannabinol
-
NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS Patent application number: 20100249223
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CANNABINOID-CONTAINING PLANT EXTRACTS AS NEUROPROTECTIVE AGENTS Patent application number: 20100239693
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Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS
-
US Patent Application 20100012118 â Medicament dosage for inhaler
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Patent 7741365 Peripheral cannabinoid receptor (CB2) selective ligands
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Patent 7816143 Oral detection test for cannabinoid use
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US Patent Application 20100204312 â METHODS AND COMPOSITIONS FOR TREATING CANCER
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Patent TW201002315 (A) â 2010-01-16 Anti-tumoural effects of cannabinoid combinations
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US Patent Application 20100158973 â THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS
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CONTROLLED-RELEASE APOPTOSIS MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS Patent application number: 20100016218
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European Patent Application EP2044935- A composition containing non-psychotropic cannabinoids for the treatment of inflammatory diseases
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Medicinal Acidic Cannabinoids US Patent 7807711B2
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US Patent Application 20110097283 â CHEWING GUM COMPOSITIONS COMPRISING CANNABINOIDS
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US Patent 7884133 B2 Cannabidiol derivatives such as 3-(2,6-dihydroxy-4-pentyl-phenyl)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, used as as analgesics, anti-inflammatory and anti-diarrheal agents
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US Patent Application 20110052694 â USE OF CANNABIDIOL PRODRUGS IN TOPICAL AND TRANSDERMAL ADMINISTRATION WITH MICRONEEDLES
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US Patent EP 2560512 A1 â Smoke and Odor Elimination Filters, Devices and Methods
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US Patent Application 20110020945 â ORAL DETECTION TEST FOR CANNABINOID USE
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US Patent Application 20110082195 â NEW USE FOR CANNABINOIDS
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Patent GB2478595 (A)â2011-09-14 Phytocannabinoids for use in the treatment of cancer
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Patent US2012052119 (A1)â2012-03-01 NANOENCAPSULATED DELTA-9-TETRAHYDROCANNABINOL
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Controlled cannabis decarboxylation â Patent US2012046352 (A1)â2012-02-23
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TRANSDERMAL DELIVERY OF CANNABINOIDS â Patent US2012034293 (A1)â2012-02-09
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Use of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy: Patent Application 20120004251
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US Patent 8106244 B2 Process for production of delta-9-tetrahydrocannabinol
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US Patent Application 20130251824 â Recycling cannabinoid extractor
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US Patent Application 20130245110 â USE FOR CANNABINOIDS (CBD/ THCV for cholesterol control)
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Transdermal delivery of cannabidiol Patent 8435556
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US Patent Application 20130280343 â Food Products Derived From Cannabinoid-Administered Livestock
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US Patent Application 20130171145 â METHODS OF TREATING LIVER DISEASE
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US Patent Application 20130059018 â PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER
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USE FOR CANNABINOIDS (Patent Cholesterol I or II diabetes, obesity, dyslipidaemia, related metabolic disorders and cardiovascular disease -
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Anti-tumoural effects of cannabinoid combinations â US 8632825 B2
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Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update
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Cannabimimetic Drugs: Recent Patents in Central Nervous System Disorders
PERINATAL HYPOXIC-ISCHEMIC INJURY (21)
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Synergistic neuroprotective therapies with hypothermia
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The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia
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The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic ischemic brain damage in mice is mediated by CB(2) and adenosine receptors
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Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia ischemia in newborn pigs
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The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia
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Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury
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Therapeutic potential of the endocannabinoid system in perinatal asphyxia
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Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke
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Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
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Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats
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Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic ischemic brain injury
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Mechanisms Of Cannabidiol Neuroprotection In Hypoxic-Ischemic Newborn Pigs: Role Of 5HT1A And CB2 Receptors
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Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuro-inflammation and apoptosis after neonatal ischemic brain damage
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Cannabinoids: well-suited candidates for the treatment of perinatal brain injury
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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
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New horizons for newborn brain protection: enhancing endogenous neuroprotection
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Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications
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Effects of Cannabidiol and Hypothermia on Short-Term Brain Damage in New-Born Piglets after Acute Hypoxia-Ischemia
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Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets
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Neuroprotective Effects of Cannabidiol In Hypoxic Ischemic Insult: The Therapeutic Window In Newborn Mice
PHARC/POLYNEUROPATHY, HEARING LOSS, ATAXIA, RETINITIS PIGMENTOSA and CATARACT SYNDROME (7)
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Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism
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The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2âarachidonoylglycerol signalling through cannabinoid receptors
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Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3
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ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC
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Two Novel Mutations in ABHD12: Expansion of the Mutation Spectrum in PHARC and Assessment of Their Functional Effects
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Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)
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Exome sequencing extends the phenotypic spectrum for ABHD12 mutations: from syndromic to nonsyndromic retinal degeneration
PLACEBO EFFECT (14)
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Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors
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Placebo-induced improvements: how therapeutic rituals affect the patientâs brain
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The Neurobiology of Placebo and Nocebo: How Expectations Influence Treatment Outcomes
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FAAH selectively influences placebo effects
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Molecular mechanisms of placebo responses in humans
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Nocebo and placebo modulation of hypobaric hypoxia headache involves the cyclo-oxygenase-prostaglandins pathway
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The sweetest pill to swallow: How patient neurobiology can be harnessed to maximise placebo effects
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Cannabinoids and Epilepsy
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Placebo and nocebo effects: a complex interplay between psychological factors and neurochemical networks
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The placebo effect: from concepts to genes
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Placebos: Honest fakery
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Placebo effect: clinical, biological and therapeutical involvements in depression
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An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain from Spinal Cord Injury and Disease
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Nature of the placebo and nocebo effect in relation to functional neurologic disorders
POISONING-HEAVY METAL (6)
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Protective effect of cannabidiol against cadmium hepatotoxicity in rats
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The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects
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Arsenic decreases antinociceptive activity of paracetamol: Possible involvement of serotonergic and endocannabinoid receptors
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Effective Phytoextraction of Cadmium (Cd) with Increasing Concentration of Total Phenolics and Free Proline in Cannabis sativa (L) Plant Under Various Treatments of Fertilizers, Plant Growth Regulators and Sodium Salt
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Differential effects and potential adverse outcomes of ionic silver and silver nanoparticles in vivo and in vitro
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Phytoaccumulation of Heavy Metals in Natural Vegetation at the Municipal Wastewater Site in Abbottabad, Pakistan
POISONING-ORGANOPHOSPHATE (18)
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Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics
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Cannabinoid Receptor Agonist WIN-55,212-2 Protects Differentiated PC12 Cells From Organophosphorus- Induced Apoptosis
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Activity-based protein profiling of organophosphorus and thiocarbamate pesticides reveals multiple serine hydrolase targets in mouse brain
-
Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice
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Effect of Developmental Chlorpyrifos Exposure on Endocannabinoid Metabolizing Enzymes in the Brain of Juvenile Rats
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Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon
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Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure
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Induction of Endocannabinoid Levels in Juvenile Rat Brain Following Developmental Chlorpyrifos Exposure
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Comparative effects of parathion and chlorpyrifos on extracellular endocannabinoid levels in rat hippocampus: Influence on cholinergic toxicity
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Low Level Chlorpyrifos Exposure Increases Anandamide Accumulation in Juvenile Rat Brain in the Absence of Brain Cholinesterase Inhibition
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Neuroactive insecticides: targets, selectivity, resistance, and secondary effects
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The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects
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The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats
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Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s)
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Fenitrothion action at the endocannabinoid system leading to spermatotoxicity in Wistar rats
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Muscarinic M1 receptor and cannabinoid CB1 receptor do not modulate paraoxon induced seizures
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COMPARATIVE EFFECTS OF PARATHION AND CHLORPYRIFOS ON ENDOCANNABINOID AND ENDOCANNABINOID-LIKE LIPID METABOLITES IN RAT STRIATUM
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Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development
POISONING-PARAQUAT (3)
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Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure
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CB2 Receptor Activation Ameliorates the Proinflammatory Activity in Acute Lung Injury Induced by Paraquat
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Determination of Herbicides Paraquat, Glyphosate, and Aminomethylphosphonic Acid in Marijuana Samples by Capillary Electrophoresis
POISONINGâROTENONE (3)
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Phytocannabinoids tetrahydrocannabinol and cannabidiol act against rotenone induced damages in murine cell cultures
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The effect of cannabis on oxidative stress and neurodegeneration induced by intrastriatal rotenone injection in rats
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Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinsonâs Disease
POLLS and SURVEYS (83)
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Survey on the use of psychotropic drugs by twelve military police units in the municipalities of Goiânia and Aparecida de Goiânia, state of Goiás, Brazil
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Survey of alcohol, tobacco, and cannabis use in the French army
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Posttraumatic stress disorder and Cannabis use in a nationally representative sample
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Prevalence and co-use of marijuana among young adult cigarette smokers: An anonymous online national survey
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Cannabis as a substitute for alcohol and other drugs: A dispensary-based survey of substitution effect in Canadian medical cannabis patients
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Prospectively Surveying Health-Related Quality of Life and Symptom Relief in a Lot Based Sample of Medical Cannabis-Using Patients in Urban Washington State Reveals Managed Chronic Illness and Debility
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A questionnaire survey of patients and carers of patients prescribed Sativex as an unlicensed medicine
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Harms and benefits associated with psychoactive drugs: findings of an international survey of active drug users
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Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment resistant epilepsy
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Clinical decisions. Medicinal use of marijuana â polling results
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Identity formation, marijuana and âthe selfâ: a study of cannabis normalization among university students
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Statistics on cannabis users skew perceptions of cannabis use
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The medicinal use of cannabis and cannabinoids-an international cross-sectional survey on administration forms
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Therapeutic benefits of cannabis: a patient survey
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A survey of synthetic cannabinoid consumption by current cannabis users
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Health Poll â Legalizing Marijuana
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Drug use, consequences and perceived accessibility in three Nigerian universities
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Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users
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Substance Use among Medical Students: A Literature Review 1988-
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Medical marijuana laws and adolescent marijuana use in the USA from 1991 to 2014: results from annual, repeated cross-sectional surveys
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A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome
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A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome
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Drugs and Crime Facts
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Cannabis in medicine: a national educational needs assessment among Canadian physicians
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State Estimates of Adolescent Marijuana Use and Perceptions of Risk of Harm From Marijuana Use:
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Prevalence and determinants of cannabinoid prescription for the management of chronic noncancer pain: a postal survey of physicians in the Abitibi-Témiscamingue region of Quebec
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High School Studentsâ Use of Electronic Cigarettes to Vaporize Cannabis
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Synthetic cannabinoid use in a nationally representative sample of US high school seniors
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Perceived risk of regular cannabis use in the United States from 2002 to 2012: Differences by sex, age, and race/ethnicity
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ADOLESCENTSâ USE OF MEDICAL MARIJUANA: A SECONDARY ANALYSIS OF MONITORING THE FUTURE DATA
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Medicinal Cannabis: A Survey Among Health Care Providers in Washington State
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Self-reported use of novel psychoactive substances in a US nationally representative survey: Prevalence, correlates, and a call for new survey methods to prevent underreporting
-
Characteristics of novel psychoactive substance exposures reported to New York City Poison Center, 2011-
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Cannabis use, depression and anxiety: A 3-year prospective population-based study
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Change in perceived risk associated with marijuana use in the United States from 2002 to
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Longitudinal Effects of School Drug Policies on Student Marijuana Use in Washington State and Victoria, Australia
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A safer alternative: Cannabis substitution as harm reduction
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Novel psychoactive substance use by US adolescents: Characteristics associated with use of synthetic cannabinoids and synthetic cathinones
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Legal issues for German-speaking cannabis growers. Results from an online survey
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Sexual identity and prevalence of alcohol and other drug use among Australians in the general population
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In the weeds: a baseline view of cannabis use among legalizing states and their neighbours
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CANNABIS: ALTERNATIVE REALITIES (CRA)
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Past 15-year trends in adolescent marijuana use: Differences by race/ethnicity and sex
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Patterns of cannabis use in patients with Inflammatory Bowel Disease: A population based analysis
-
Online survey characterizing vaporizer use among cannabis users
-
Marijuana experiences, voting behaviors, and early perspectives regarding marijuana legalization among college students from 2 states
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Prioritizing Alcohol Prevention: Establishing Alcohol as the Gateway Drug and Linking Age of First Drink With Illicit Drug Use
-
Adult attention deficit hyperactivity disorder symptom profiles and concurrent problems with alcohol and cannabis: sex differences in a representative, population survey
-
Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32â330 subjects from the International Cannabis Consortium
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The Role of Medicinal Cannabis in Clinical Therapy: Pharmacistsâ Perspectives
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Attitudes of Israeli Rheumatologists to the Use of Medical Cannabis as Therapy for Rheumatic Disorders
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Socio-Demographic Factors Associated with Psychoactive Substance Use among Commercial Motorcycle Operators in Kano, Nigeria
-
National Estimates of Marijuana Use and Related Indicators â National Survey on Drug Use and Health, United States, 2002â
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Highlights of the 2011 Drug Abuse Warning Network (DAWN) Findings on Drug Related Emergency Department Visits
-
Effectiveness of the synthetic cannabinoids seminar
-
Minnesota Pharmacists and Medical Cannabis: A Survey of Knowledge, Concerns, and Interest Prior to Program Launch
-
Marijuana: Views on Its Medical Use Recorded at the Slovak Social Network
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Opinions of Hospital Pharmacists in Canada Regarding Marijuana for Medical Purposes
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American Attitudes toward Substance Use in the United States
-
COMPREHENSIVE MEDICAL MARIJUANA PATIENT STUDY
-
Comparing adults who use cannabis medically with those who use recreationally: Results from a national sample
-
Pediatric oncology providers and use of medical marijuana in children with cancer
-
New Zealand Health Survey 2012/13: characteristics of medicinal cannabis users
-
The association between cannabis use and anxiety disorders: Results from a population based representative sample
-
A comparison between wastewater-based drug data and an illicit drug use survey in a selected community
-
Early Survey Results from the Minnesota Medical Cannabis Program
-
Clinical trials of medicinal cannabis for appetite-related symptoms from advanced cancer: A survey of preferences, attitudes and beliefs among patients willing to consider participation
-
Risky substance use and peer pressure in Swiss young men: Test of moderation effects
-
The replicability of cannabis use prevalence estimates in the United States
-
Bongs and baby boomers: Trends in cannabis use among older Australians
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Determining Cannabis Use Status From a Photograph: An Assessment of the âJay-darâ in Neuropsychologists
-
Survey of herbal cannabis (marijuana) use in rheumatology clinic attenders with a rheumatologist confirmed diagnosis
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Got Munchies? Estimating the Relationship between Marijuana Use and Body Mass Index
-
Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis
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Demographic trends among older cannabis users in the United States, 2006â13
-
The association between cannabis use and motivation and intentions to quit tobacco within a sample of Australian socioeconomically disadvantaged smokers
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Is the Legalization of Marijuana Associated With Its Use by Adolescents?
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Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis
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Substance Use, Health, and Functioning Characteristics of Medical Marijuana Program Participants Compared to the General Adult Population in Ontario (Canada)
-
Irish general practitioner attitudes toward decriminalisation and medical use of cannabis: results from a national survey
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Expertsâ Perspectives on the Role of Medical Marijuana in Oncology: a semi-structured interview study
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Support for Marijuana Legalization and Predictors of Intentions to Use Marijuana More Often in Response to Legalization Among U.S. Young Adults
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Do recreational cannabis users, unlicensed and licensed medical cannabis users form distinct groups?
POLLUTION/ENVIRONMENT (11)
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Drugs of abuse in airborne particulates in urban environments
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Potential exposures associated with indoor marijuana growing operations
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Cannabis, Pesticides and Conflicting Laws: the Dilemma for Legalized States and Implications for Public Health
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Effective Phytoextraction of Cadmium (Cd) with Increasing Concentration of Total Phenolics and Free Proline in Cannabis sativa (L) Plant Under Various Treatments of Fertilizers, Plant Growth Regulators and Sodium Salt
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Impacts of surface water diversions for marijuana cultivation on aquatic habitat in four northwestern California watersheds
-
Patterns of Natural and Human-Caused Mortality Factors of a Rare Forest Carnivore, the Fisher (Pekania pennanti) in California
-
Phytoaccumulation of Heavy Metals in Natural Vegetation at the Municipal Wastewater Site in Abbottabad, Pakistan
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High Time for Conservation: Adding the Environment to the Debate on Marijuana Liberalization
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The increase of cannabis use may indirectly affect the health status of a freshwater species
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Phytoextraction of heavy metals by potential native plants and their microscopic observation of root growing on stabilised distillery sludge as a prospective tool for in situ phytoremediation of industrial waste
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Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain
POST-OPERATIVE PAIN (9)
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Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain
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Historical essay: An Arabic surgeon, Ibn al Quffâs (1232-1286) account on surgical pain relief
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Peripheral and Spinal Activation of Cannabinoid Receptors by Joint Mobilization Alleviates Postoperative Pain in Mice
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Postoperative Analgesia in the Jamaican Cannabis User
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Intrathecal Injection of JWH015 Attenuates Remifentanil-Induced Postoperative Hyperalgesia by Inhibiting Activation of Spinal Glia in a Rat Model
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Interaction of a Cannabinoid-2 Agonist With Tramadol on Nociceptive Thresholds and Immune Responses in a Rat Model of Incisional Pain
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Endocannabinoids and acute pain after total knee arthroplasty
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The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report
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Effect of endocannabinoid degradation on pain: role of FAAH polymorphisms in experimental and postoperative pain in women treated for breast cancer
POST-TRAUMATIC STRESS DISORDER/FEAR EXTINCTION (136)
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The use of Cannnabidiol (CBD) and Meditation to reduce Binge Drinking, Anxiety and to improve Emotional Regulation in Long Term Behavior Therapy
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PTSD contributes to teen and young adult cannabis use disorders
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Endocannabinoids and psychiatric disorders: the road ahead
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Cannabinoids modulate hippocampal memory and plasticity
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The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program
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The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus
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Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress
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Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm
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Posttraumatic Stress and Marijuana Use Coping Motives: The Mediating Role of Distress Tolerance
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Posttraumatic stress disorder and Cannabis use in a nationally representative sample
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Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brain stem after repeated stress: Implication for PTSD and drug abuse
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Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats
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Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study
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Cannabis use among military veterans after residential treatment for posttraumatic stress disorder
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Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
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Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats
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Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
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Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
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Bimodal Control of Fear-Coping Strategies by CB1 Cannabinoid Receptors
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On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment
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Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1
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CADTH Rapid Response Report: Cannabinoids for the treatment of post-traumatic stress disorder
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Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress
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Fear relief-toward a new conceptual frame work and what endocannabinoids gotta do with it
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Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo
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Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear
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Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence
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Prevalence of Cannabis Use Disorder Diagnoses Among Veterans in 2002, 2008, and 2009
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The underdiagnosis of cannabis use disorders and other Axis-I disorders among military veterans within VHA
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Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin?
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Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors
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CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning
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Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors
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Positron emission tomography offers new perspectives for evidence-based treatment development in PTSD
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Plasma concentrations of endocannabinoids and related primary Fatty Acid amides in patients with post-traumatic stress disorder
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Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study
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Cannabinoid modulation of chronic mild stress-induced selective enhancement of trace fear conditioning in adolescent rats
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The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD)
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Recent Progress in Understanding the Pathophysiology of Post-Traumatic Stress Disorder: Implications for Targeted Pharmacological Treatment
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Translational evidence for the involvement of the endocannabinoid system in stress related psychiatric illnesses
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Cannabinoid facilitation of fear extinction memory recall in humans
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Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor
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The endocannabinoid system and emotional processing: A pharmacological fMRI study with â9-tetrahydrocannabinol
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Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks
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Amygdala FAAH and anandamide: mediating protection and recovery from stress
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Using cannabis to help you sleep: Heightened frequency of medical cannabis use among those with PTSD
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Toward Rational Pharmacotherapy for Posttraumatic Stress Disorder: Reprise
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Correspondence (letter to the editor): Cannabis Therapy
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The endocannabinoid system provides an avenue for evidence-based treatment development for PTSD.
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A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: Potential extinction enhancers
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Predator threat stress promotes long lasting anxiety-like behaviors and modulates synaptophysin and CB1 receptors expression in brain areas associated with PTSD symptoms
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Cannabidiol enhances consolidation of explicit fear extinction in humans
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Cannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit
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Infusion of cannabidiol into infralimbic cortex facilitates fear extinction via CB1 receptors
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Cannabinoids and glucocorticoids modulate emotional memory after stress
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Effects of endocannabinoid and endovanilloid systems on aversive memory extinction
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Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders
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Posttraumatic stress disorder and cannabis use characteristics among military veterans with cannabis dependence
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PTSD Symptom Reports of Patients Evaluated for the New Mexico Medical Cannabis Program
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Impaired Fear Memory Specificity Associated with Deficient EndocannabinoidDependent Long-Term Plasticity
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Translational evidence for a role of endocannabinoids in the etiology and treatment of posttraumatic stress disorder
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Cannabinoid Modulation of Amygdala Subregion Functional Connectivity to Social Signals of Threat
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Cannabinoid Transmission in the Prefrontal Cortex Bi-Phasically Controls Emotional Memory Formation via Functional Interactions with the Ventral Tegmental Area
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Use of a Synthetic Cannabinoid in a Correctional Population for Post-traumatic Stress Disorder-Related Insomnia and Nightmares, Chronic Pain, Harm Reduction, and Other Indications: A Retrospective Evaluation
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Stress regulates endocannabinoid-CB1 receptor signaling
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Drug discovery strategies that focus on the endocannabinoid signaling system in psychiatric disease
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Cannabinoid Type 1 Receptor Availability in the Amygdala Mediates Threat Processing in Trauma Survivors
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Positive posttraumatic stress disorder screens among first-time medical cannabis patients: Prevalence and association with other substance use
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Interaction between the Cholecystokinin and Endogenous Cannabinoid Systems in Cued Fear Expression and Extinction Retention
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Toward a translational approach to targeting the endocannabinoid system in post-traumatic stress disorder: A critical review of preclinical research
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Cannabinoid modulation of prefrontal-limbic activation during fear extinction learning and recall in humans
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Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
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Cannabinoids Prevent the Effects of a Footshock Followed by Situational Reminders on Emotional Processing
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Modulation of the extinction of fear learning
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When time stands still: an integrative review on the role of chronodisruption in post-traumatic stress disorder
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Marijuana, expectancies, and post-traumatic stress symptoms: a preliminary investigation
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The interaction between serotonergic and cannabinoidergic modulations involved in the fear extinction
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Preliminary, open-label, pilot study of add-on oral δ(9)-tetrahydrocannabinol in chronic post-traumatic stress disorder
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The learning of fear extinction
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PTSD Growth and Substance Abuse Among a College Student Community: Coping Strategies after 2009 Lâaquila Earthquake
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Increased contextual fear conditioning in iNOS knockout mice: additional evidence for the involvement of nitric oxide in stress-related disorders and contribution of the endocannabinoid system
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The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study
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Metabolite profiling in posttraumatic stress disorder
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Training-Associated Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats
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The endocannabinoid system in guarding against fear, anxiety and stress
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Cannabidiol as a Potential Treatment for Anxiety Disorders
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β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling
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Anxiety, Stress, and Fear Response in Mice with Reduced Endocannabinoid Levels
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Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey
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Investigational drugs under development for the treatment of PTSD
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Î9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption
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2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons
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Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-endoccannabinoid receptor in the ventral mesencephalon
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The influence of cannabinoids on learning and memory processes of the dorsal striatum
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Use and effects of cannabinoids in military veterans with posttraumatic stress disorder
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Providing a food reward reduces inhibitory avoidance learning in zebrafish
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Endocannabinoids and Mental Disorders
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Modulation of cannabinoid signaling by amygdala α2-adrenergic system in fear conditioning
-
Dorsolateral periaqueductal gray matter CB1 and TRPV1 receptors exert opposite modulation on expression of contextual fear conditioning
-
Marijuana dependence moderates the effect of posttraumatic stress disorder on trauma cue reactivity in substance dependent patients
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Being the Victim of Violence during a Date predicts Next-Day Cannabis Use among Female College Students
-
Î9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption
-
Cannabinoid Receptors May Control Aversive Memories
-
CB2 Cannabinoid Receptor Knockout in Mice Impairs Contextual Long-Term Memory and Enhances Spatial Working Memory
-
2-arachidonoylglycerol signaling impairs short-term fear extinction
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Modulation of Fear Extinction by Stress, Stress Hormones and Estradiol: A Review
-
Cannabis use among Navy personnel in Sri Lanka: a cross sectional study
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Cannabis for posttraumatic stress disorder: A neurobiological approach to treatment
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Cyclooxygenase-2 inhibition reduces stress-induced affective pathology
-
Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders
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PTSD: from neurobiology to pharmacological treatments
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Cannabidiol Regulation of Learned Fear: Implications for Treating Anxiety-Related Disorders
-
Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid
-
Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning
-
Bidirectional Effects of Cannabidiol on Contextual Fear Memory Extinction
-
Medical use of cannabis products : Lessons to be learned from Israel and Canada
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Sex differences in hippocampal response to endocannabinoids after exposure to severe stress
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Endocannabinoid concentrations in hair are associated with PTSD symptom severity
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The association of specific traumatic experiences with cannabis initiation and transition to problem use: Differences between African-American and European-American women
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CB1 cannabinoid receptor-mediated anandamide signalling reduces the defensive behaviour evoked through GABAA receptor blockade in the dorsomedial division of the ventromedial hypothalamus
-
Associations of Posttraumatic Stress Disorder Symptoms With Marijuana and Synthetic Cannabis Use Among Young Adult U.S. Veterans: A Pilot Investigation
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Cannabidiol Modulates Fear Memory Formation through Interactions with Serotonergic Transmission in the Mesolimbic System
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The endocannabinoid system and Post Traumatic Stress Disorder (PTSD): From preclinical findings to innovative therapeutic approaches in clinical settings
-
Factors associated with having a medical marijuana card among Veterans with recent substance use in VA outpatient treatment
-
Understanding resilience: New approaches for preventing and treating PTSD
-
Cannabinoids and post-traumatic stress disorder: clinical and preclinical evidence for treatment and prevention
-
Dorsal hippocampus cannabinoid type 1 receptors modulate the expression of contextual fear conditioning in rats: Involvement of local glutamatergic/nitrergic and GABAergic neurotransmissions
-
Cannabinoid CB1 receptors in distinct circuits of the extended amygdala determine fear responsiveness to unpredictable threat
-
FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence
-
Targeting the Endocannabinoid System in Psychiatric Illness
-
Regulation of fear extinction by long-term depression: the roles of endocannabinoids and brain derived neurotrophic factor
-
Considering Future Pharmacotherapy for PTSD
-
Cannabinoid modulation of zebrafish fear learning and its functional analysis investigated by c-Fos expression
-
Marijuana Could Help Treat Drug Addiction and Mental Health Problems
-
Medicinal versus recreational cannabis use: Patterns of cannabis use, alcohol use, and cued-arousal among veterans who screen positive for PTSD
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The involvement of cannabinoids and mTOR in the reconsolidation of an emotional memory in the hippocampal-amygdala-insular circuit
POTENCY (56)
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Potency trends of Î9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008
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How Accurate is Potency Testing?
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The Effect of Electrical Lighting Power and Irradiance on Indoor-Grown Cannabis Potency and Yield
-
Is todayâs marijuana more potent simply because itâs fresher?
-
A survey of the potency of Japanese illicit cannabis in fiscal year 2010
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Evolution of the Content of THC and Other Major Cannabinoids in Drug-Type Cannabis Cuttings and Seedlings During Growth of Plants
-
First systematic evaluation of the potency of Cannabis sativa plants grown in Albania
-
Cannabis Strain Explorer
-
Michael Pollan: What Do Marijuana and Catnip Have in Common?
-
Analysis of Cannabis Seizures in NSW, Australia: Cannabis Potency and Cannabinoid Profile
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Cannabis, a complex plant: different compounds and different effects on individuals
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Cannabis affects people differently: inter-subject variation in the psychotogenic effects of Î9-tetrahydrocannabinol: a functional magnetic resonance imaging study with healthy volunteers
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THE EFFECT OF ABA ON PIGMENTS AND TETRAHYDROCANNABINOL IN CANNABIS SATIVA AT FLOWERING STAGE
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Variability of cannabis potency in the Venice area (Italy): A survey over the period 2010-
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Variability of cannabis potency in the Venice area (Italy): A survey over the period 2010-
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Cross-sectional and prospective relation of cannabis potency, dosing and smoking behaviour with cannabis dependence: an ecological study
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Cross-sectional and prospective relation of cannabis potency, dosing and smoking behaviour with cannabis dependence: an ecological study
-
Therapeutic Satisfaction and Subjective Effects of Different Strains of Pharmaceutical Grade Cannabis
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Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users
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Just say âknowâ: how do cannabinoid concentrations influence usersâ estimates of cannabis potency and the amount they roll in joints?
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Acute subjective effects after smoking joints containing up to 69 mg Î9-tetrahydro-cannabinol in recreational users: a randomized, crossover clinical trial
-
Selective monoacylglycerol lipase inhibitors: Antinociceptive vs cannabimimetic effects in mice
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No smoke, no fire: What the initial literature suggests regarding vapourized cannabis and respiratory risk
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Î9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market
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Î9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market
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Marijuana gears up for production high in US labs
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Cannabinoid Dose and Label Accuracy in Edible Medical Cannabis Products
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Potency 101
-
Metabolism of classical cannabinoids and the synthetic cannabinoid JWH-018
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Sequence heterogeneity of cannabidiolic- and tetrahydrocannabinolic acid-synthase in Cannabis sativa L. and its relationship with chemical phenotype
-
Effect of induced polyploidy on some biochemical parameters in Cannabis sativa L
-
Evaluation of elemental profiling methods, including laser-induced breakdown spectroscopy (LIBS), for the differentiation of Cannabis plant material grown in different nutrient solutions
-
(1)H NMR and HPLC/DAD for Cannabis sativa L. chemotype distinction, extract profiling and specification
-
Potency trends of Î9 -THC, cannabidiol and cannabinol in cannabis in the Netherlands: 2005-
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Determination of the relative percentage distribution of THCA and Î9-THC in herbal cannabis seized in Austria â Impact of different storage temperatures on stability
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Tetrahydrocannabinol pharmacokinetics, new synthetic cannabinoids, road safety and cannabis
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Legal regulated markets have the potential to reduce population levels of harm associated with cannabis use
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Evaluating the Effects of Gamma-Irradiation for Decontamination of Medicinal Cannabis
-
Drug vaping applied to cannabis: Is âCannavapingâ a therapeutic alternative to marijuana?
-
Evaluation of Two Commercially Available Cannabidiol Formulations for Use in Electronic Cigarettes
-
Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines
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Traditional marijuana, high-potency cannabis and synthetic cannabinoids: increasing risk for psychosis
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Use of marijuana for medical purposes (click âFull Text Linksâ for
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Analysis of a commerical marijuana e-cigarette formulation
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Changes in cannabis potency over the last two decades (1995-
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Cannabinoids for treatment of glaucoma
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Cannabis-induced psychosis associated with high potency âwax dabsâ
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Analysis of a Commercial Marijuana e-Cigarette Formulation
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âThose edibles hit hardâ: Exploration of Twitter data on cannabis edibles in the U.S.
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Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons
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Enhanced discriminative stimulus effects of Î9-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys
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Limitations to the Dutch cannabis toleration policy: Assumptions underlying the reclassification of cannabis above 15% THC
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Stability of Tetrahydrocannabinol and Cannabidiol in Prepared Quality Control Medible Brownies
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A study of cannabis potency in France over a 25 years period (1992-
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Cannabinoid concentrations in Canadaâs regulated medical cannabis industry
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Comparison of the discriminative stimulus and response rate effects of Î9- tetrahydrocannabinol and synthetic cannabinoids in female and male rats
PREGNANCY/PRENATAL EXPOSURE (102)
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The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure
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N-Acylethanolamine Levels and Expression of Their Metabolizing Enzymes during Pregnancy
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Effects of abnormal cannabidiol on oxytocin-induced myometrial contractility
-
Cannabinoids and Reproduction: A Lasting and Intriguing History
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From Fertilisation to Implantation in Mammalian Pregnancy-Modulation of Early Human Reproduction by the Endocannabinoid System
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A prospective study on intrauterine cannabis exposure and fetal blood flow
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Tocolytic Effect of Î9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide-Induced Preterm Delivery: Role of Nitric Oxide
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Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle
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A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with preeclampsia in the Central European population
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Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study
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Endocannabinoids and pregnancy
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Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed
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Sex difference in cell proliferation in developing rat amygdala mediated by endo-cannabinoids has implications for social behavior
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Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implications
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The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility
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Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS
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Modulation of the novel cannabinoid receptor â GPR55 â during rat fetoplacental development
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Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea?
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Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy
-
Endocannabinoid signaling in female reproduction
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Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos
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Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes
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Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier
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Endocannabinoids via CBâ receptors act as neurogenic niche cues during cortical development
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Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure
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Cannabinoid modulation of mother-infant interaction: is it just about milk?
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Elevated Anandamide and Related N-Acylethanolamine Levels Occur in the Peripheral Blood of Women With Ectopic Pregnancy and Are Mirrored by Changes in Peripheral Fatty Acid Amide Hydrolase Activity
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Detection of In Utero Marijuana Exposure by GCâMS, Ultra-Sensitive ELISA and LCâTOFâMS Using Umbilical Cord Tissue
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The role of endocannabinoids in pregnancy
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Embryonic diapause in humans: time to consider?
-
The Effect of Mifepristone (RU486) on the Endocannabinoid System in Human Plasma and First Trimester Trophoblast of Women undergoing Termination of Pregnancy
-
Synthetic cannabinoids and potential reproductive consequences
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Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis
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Of mice and (wo)men: factors influencing successful implantation including endocannabinoids
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Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity
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Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity
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Long-term consequences of perinatal fatty acid amino hydrolase inhibition
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Differential expression of endocannabinoid system in normal and preeclamptic placentas: Effects on nitric oxide synthesis
-
Detection of the endocannabinoid metabolome in human plasma and breast milk
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Endocannabinoid receptor (CB1R) deficiency affects maternal care and alters the damâs hippocampal oxytocin receptor and BDNF expression
-
Diagnostic Value of Concentration Profiles of Glucocorticosteroids and Endocannabinoids in Hair
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Plasma Anandamide and Related N-acylethanolamide Levels are not Elevated in Pregnancies Complicated by Hyperemesis Gravidarum
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Increased placental expression of cannabinoid receptor 1 in preeclampsia: an observational study
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The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: Involvement of both mitochondrial and death receptor pathways
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The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: Involvement of both mitochondrial and death receptor pathways
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Endocannabinoids as biomarkers of human reproduction
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Endocannabinoid Regulation in Human Endometrium Across the Menstrual Cycle
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Fatty Acid Binding Protein-4 is expressed in the mouse placental labyrinth, yet is dispensable for placental triglyceride accumulation and fetal growth
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Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis
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Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis
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Activity of anandamide (AEA) metabolic enzymes in rat placental bed
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Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
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Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
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Contribution of in utero drug exposure when interpreting hair results in young children
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Local uterine Ang-(1-7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats
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Increased Plasma Levels of FABP4 and PTEN Is Associated with More Severe Insulin Resistance in Women with Gestational Diabetes Mellitus
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Decreased circulating anandamide levels in preeclampsia
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Lipid mediator profile in vernix caseosa reflects skin barrier development
-
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta
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Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta
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A role for GPR55 in human placental venous endothelial cells
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Use of paracetamol during pregnancy and child neurological development
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Dynamics of expression and localization of the cannabinoid system in granulosa cells during oocyte nuclear maturation
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Role of the endocannabinoid system in the mechanisms involved in the LPS-induced preterm labor
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Progesterone and anandamide in pregnancy loss
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Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drugâs harm to children and adults, but the scientific evidence is seldom clear-cut
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Participation of the endocannabinoid system (ECS) in the weight-gain and sensitization to LPS exposure in a maternal obesity model
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CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Î9-tetrahydrocannabinol
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[268-POS]: Placental expression of the endocannabinoid system in preeclampsia
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[16-OR]: Vasoactive lipid mediators control uterine vascular reactivity at early pregnancy in the transgenic hAGNxhREN rat
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Endocannabinoid Levels in Newborns in Relation to the Mode of Delivery
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Lipopolysaccharide-induced murine embryonic resorption involves changes in endo-cannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion
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Anandamide restricts uterine stromal differentiation and is critical for complete decidualization
-
Maternal marijuana use and neonatal morbidity
-
The endocannabinoid anandamide affects the synthesis of human syncytiotrophoblast related proteins
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Association between marijuana use and adverse obstetrical and neonatal outcomes
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Marijuana use and pregnancy: prevalence, associated characteristics, and birth outcomes
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Maternal age and trajectories of cannabis use
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Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring
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Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth
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Differential Regulation of Eicosanoid and Endocannabinoid Production by Inflammatory Mediators in Human Choriodecidua
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Maternal marijuana use has independent effects on risk for spontaneous preterm birth but not other common late pregnancy complications
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Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid
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Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring
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Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring
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Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release
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The endocannabinoid system: an emergent player in human placentation
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Alcohol, Methamphetamine, and Marijuana Exposure Have Distinct Effects on the Human Placenta
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Conceptus development and transcriptome at preimplantation stages in lactating dairy cows of distinct genetic groups and estrous cyclic statuses
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Expression analysis of cannabinoid receptors 1 and 2 in B cells during pregnancy and their role on cytokine production
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Dietary conjugated linoleic acid supplementation alters the expression of genes involved in the endocannabinoid system in the bovine endometrium and increases plasma progesterone concentrations
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Heparin exerts anti-apoptotic effects on uterine explants by targeting the endocannabinoid system
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A role for the endocannabinoid system in premature luteal regression and progesterone withdrawal in lipopolysaccharide-induced early pregnancy loss model
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Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor- 1
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The endocannabinoid anandamide impairs in vitro decidualization of human cells
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Sexually-dimorphic alterations in cannabinoid receptor density depend upon prenatal / early postnatal history
-
Bisphenol A induces hypothalamic down-regulation of CB1 and anorexigenic effects in male mice
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Peripheral Blood Mononuclear Cells Infiltration Downregulates Decidual FAAH Activity in an LPS-Induced Embryo Resorption Model
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A role for the endocannabinoid system in premature luteal regression and progesterone withdrawal in lipopolysaccharide-induced early pregnancy loss model
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Evaluating a switch from meconium to umbilical cord tissue for newborn drug testing: A retrospective study at an academic medical center
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Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity
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Developmental Patterns of Adolescent Marijuana and Alcohol Use and Their Joint Association with Sexual Risk Behavior and Outcomes in Young Adulthood
PROSTATIC HYPERPLASIA/BPH/ENLARGED PROSTATE GLAND (5)
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Transient receptor potential A1 and cannabinoid receptor activity in human normal and hyperplastic prostate: relation to nerves and interstitial cells
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Distribution and Possible Function of Cannabinoid Receptor Subtype 1 in the Human Prostate*âAn Inhibitory Role for Growth in the Human Prostate Cancer
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Future direction in pharmacotherapy for non-neurogenic male lower urinary tract symptoms
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Stimulation of cannabinoid receptors by using Rubus coreanus extracts to control osteoporosis in aged male rats
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A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome
PRURITIS (22)
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The Management of Chronic Pruritus in the Elderly
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CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action
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Is there a legitimate role for the therapeutic use of cannabinoids for symptom management in chronic kidney disease?
-
Endocannabinoid signaling and epidermal differentiation
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Differences in peripheral endocannabinoid modulation of scratching behavior in facial vs spinally-innervated skin
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Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent
-
Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent
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On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation
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Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats
-
Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with trauma
-
Evaluation of sex differences in cannabinoid dependence
-
Blockade of cannabinoid CB1 and CB2 receptors does not prevent the antipruritic effect of systemic paracetamol
-
The effect of propofol on intrathecal morphine-induced pruritus and its mechanism
-
Cannabinoid 1 receptors in keratinocytes attenuate FITC-induced mouse atopic-like dermatitis
-
Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase
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S-777469, a Novel Cannabinoid Type 2 Receptor Agonist, Suppresses Itch-Associated Scratching Behavior in Rodents through Inhibition of Itch Signal Transmission
-
Uremic Pruritus Is Not Associated with Endocannabinoid Receptor 1 Gene Polymorphisms
-
The Gut-Itch Connection
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Systemic and spinal administration of FAAH, MAGL inhibitors and dual FAAH/MAGL inhibitors produce antipruritic effect in mice
-
Cannabis and Dr Piffard-A Century Ahead of the Curve
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Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis
-
The Endocannabinoid System and Its Role in Eczematous Dermatoses
PSORIASIS (10)
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Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS
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Endocannabinoid signaling and epidermal differentiation.
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Cannabinoid Treatment for Psoriasis Symptoms
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A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ
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Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in psoriasis patients
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Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?
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Selective Cannabinoid Receptor-1 Agonists Regulate Mast Cell Activation in an Oxazolone-Induced Atopic Dermatitis Model
-
Cannabis for refractory psoriasis-high hopes for a novel treatment and a literature review
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Anandamide Suppresses Proinflammatory T Cell Responses In Vitro through Type-1 Cannabinoid Receptor-Mediated mTOR Inhibition in Human Keratinocytes
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Cannabinoids: Possible agents for treatment of psoriasis via suppression of angiogenesis and inflammation